IR@PKUHSC  > 北京大学第二临床医学院
学科主题临床医学
Prevalence of microvascular diseases among tertiary care Chinese with early versus late onset of type 2 diabetes
Li, Ling1; Ji, Linong2; Guo, Xiaohui3; Ji, Qiuhe4; Gu, Weijun5; Zhi, Xinyue1; Li, Xing6; Kuang, Hongyu7; Su, Benli8; Yan, Jinhua9; Yang, Xilin1
关键词Chinese Early-onset Microvascular Diseases Prevalence Type 2 Diabetes Mellitus
刊名JOURNAL OF DIABETES AND ITS COMPLICATIONS
2015
DOI10.1016/j.jdiacomp.2014.08.010
29期:1页:32-37
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Endocrinology & Metabolism
研究领域[WOS]Endocrinology & Metabolism
关键词[WOS]IMPAIRED GLUCOSE-TOLERANCE ; BLOOD-GLUCOSE ; RISK-FACTORS ; LIFE-STYLE ; COMPLICATIONS ; YOUNG ; MELLITUS ; ASSOCIATION ; RETINOPATHY ; PREVENTION
英文摘要

Aims: This study aimed to investigate the impact of early-onset diabetes on the risk of microvascular diseases in Chinese with type 2 diabetes mellitus (T2DM).

Methods: A cross sectional survey of 29,442 patients with T2DM in 77 tertiary hospitals in China was conducted in 2011. Early-onset diabetes was defined as diagnosis of diabetes before 40 years of age. Microvascular complications and risk factors were documented. Prevalence of microvascular disease was standardized to the Chinese population in 2010. Logistic regression analysis was performed to obtain odds ratios (OR) for early versus late onset of T2DM.

Results: A total of 1,303 (4.4%) patients had nephropathy, 2,137 (7.3%) had retinopathy and 3,012 (10.2%) had either of them. Early-onset diabetes greatly increased the prevalence of microvascular diseases compared with late-onset diabetes (nephropathy: 5.1% vs. 1.5%; retinopathy: 7.1% vs. 2.7%; either: 9.7% vs. 3.6%), especially among patients from 45 to 59 years of age. After adjusting for age and sex, patients with early-onset T2DM were at 1.69-fold (95% CI 1.46-1.95) higher risk of microvascular diseases than those with late-onset T2DM. However, this was not significant after adjusting for traditional risk factors and disease duration (p = 0.162).

Conclusion: Chinese patients with early-onset T2DM are at a marked increased risk of microvascular diseases. (C) 2015 Elsevier Inc. All rights reserved.

语种英语
WOS记录号WOS:000348244400007
资助机构Novo Nordisk China
引用统计
被引频次:14[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/55637
专题北京大学第二临床医学院
北京大学第一临床医学院_内分泌内科
作者单位1.Tianjin Med Univ, Sch Publ Hlth, Dept Epidemiol & Biostat, Tianjin 300070, Peoples R China
2.Peking Univ, Peoples Hosp, Dept Endocrinol & Metab, Beijing 100871, Peoples R China
3.Peking Univ, Hosp 1, Dept Endocrinol, Beijing 100871, Peoples R China
4.4th Mil Med Univ, Xijing Hosp, Dept Endocrinol, Xian, Peoples R China
5.Chinese Peoples Liberat Army Gen Hosp, Dept Endocrinol, Beijing, Peoples R China
6.Shanxi Med Univ, Hosp 2, Dept Endocrinol, Taiyuan, Peoples R China
7.Harbin Med Univ, Affiliated Hosp 1, Dept Endocrinol, Harbin, Peoples R China
8.Dalian Med Univ, Affiliated Hosp 2, Dept Endocrinol, Dalian, Peoples R China
9.Sun Yat Sen Univ, Affiliated Hosp 3, Dept Endocrinol, Guangzhou 510275, Guangdong, Peoples R China
推荐引用方式
GB/T 7714
Li, Ling,Ji, Linong,Guo, Xiaohui,et al. Prevalence of microvascular diseases among tertiary care Chinese with early versus late onset of type 2 diabetes[J]. JOURNAL OF DIABETES AND ITS COMPLICATIONS,2015,29(1):32-37.
APA Li, Ling.,Ji, Linong.,Guo, Xiaohui.,Ji, Qiuhe.,Gu, Weijun.,...&Yang, Xilin.(2015).Prevalence of microvascular diseases among tertiary care Chinese with early versus late onset of type 2 diabetes.JOURNAL OF DIABETES AND ITS COMPLICATIONS,29(1),32-37.
MLA Li, Ling,et al."Prevalence of microvascular diseases among tertiary care Chinese with early versus late onset of type 2 diabetes".JOURNAL OF DIABETES AND ITS COMPLICATIONS 29.1(2015):32-37.
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