|Ambulatory arterial stiffness index correlates with ambulatory pulse pressure but not dipping status in patients with grade 1/grade 2 essential hypertension|
|Qin, Tingli1; Jiang, Hong1; Jiao, Yuan1; Ke, Yuannan1; Sun, Ningling2; Wang, Jiguang3; Zhu, Junren4|
|关键词||Ambulatory Blood Pressure Monitoring Ambulatory Arterial Stiffness Index Blood Pressure Variability Morning Blood Pressure Surge Pulse Pressure|
|刊名||JOURNAL OF INTERNATIONAL MEDICAL RESEARCH|
|WOS标题词||Science & Technology|
|类目[WOS]||Medicine, Research & Experimental ; Pharmacology & Pharmacy|
|研究领域[WOS]||Research & Experimental Medicine ; Pharmacology & Pharmacy|
|关键词[WOS]||TARGET ORGAN DAMAGE ; GLOMERULAR-FILTRATION-RATE ; BLOOD-PRESSURE ; CARDIOVASCULAR MORTALITY ; PROGNOSTIC-SIGNIFICANCE ; RENAL-FUNCTION ; ASSOCIATION ; REPRODUCIBILITY ; VARIABILITY ; PREDICTOR|
Objective: To evaluate the relationship between ambulatory arterial stiffness index (AASI) and other parameters derived from ambulatory blood pressure (BP) monitoring, including dipping status, in patients with grade 1/grade 2 hypertension.
Methods: This retrospective analysis included baseline data from Chinese outpatients enrolled into a previous study, who had clinic diastolic BP of 90-109mmHg and systolic BP < 180 mmHg, had undergone 24-h ambulatory BP monitoring and routine blood chemistry investigations, and had estimated glomerular filtration rate (eGFR) data.
Results: Out of 120 patients screened, 87 were included. No significant difference in 24-h AASI was found between dippers and nondippers. The 24-h AASI significantly correlated with age, systolic BP and pulse pressure, and inversely correlated with 24-h diastolic BP variation and eGFR. In dippers and nondippers, AASI correlated with daytime pulse pressure, daytime diastolic BP variation and eGFR; in nondippers, AASI also correlated with 24-h systolic BP and 24-h pulse pressure. The 24-h AASI was significantly associated with 24-h pulse pressure and daytime pulse pressure.
Conclusion: In patients with grade 1/grade 2 essential hypertension, AASI shows a significant correlation with ambulatory pulse pressure.
|作者单位||1.China Japan Friendship Hosp, Dept Cardiol, Beijing 100029, Peoples R China|
2.Peking Univ, Peoples Hosp, Dept Cardiol, Beijing 100871, Peoples R China
3.Shanghai Jiao Tong Univ, Sch Med, Ctr Epidemiol Studies & Clin Trials, Shanghai Inst Hypertens,Ruijin Hosp, Shanghai 200030, Peoples R China
4.Fudan Univ, Zhongshan Hosp, Dept Cardiol, Shanghai 200433, Peoples R China
|Qin, Tingli,Jiang, Hong,Jiao, Yuan,et al. Ambulatory arterial stiffness index correlates with ambulatory pulse pressure but not dipping status in patients with grade 1/grade 2 essential hypertension[J]. JOURNAL OF INTERNATIONAL MEDICAL RESEARCH,2014,42(6):1323-1334.|
|APA||Qin, Tingli.,Jiang, Hong.,Jiao, Yuan.,Ke, Yuannan.,Sun, Ningling.,...&Zhu, Junren.(2014).Ambulatory arterial stiffness index correlates with ambulatory pulse pressure but not dipping status in patients with grade 1/grade 2 essential hypertension.JOURNAL OF INTERNATIONAL MEDICAL RESEARCH,42(6),1323-1334.|
|MLA||Qin, Tingli,et al."Ambulatory arterial stiffness index correlates with ambulatory pulse pressure but not dipping status in patients with grade 1/grade 2 essential hypertension".JOURNAL OF INTERNATIONAL MEDICAL RESEARCH 42.6(2014):1323-1334.|