学科主题药学
Design and synthesis of novel multivalent mannosides targeting the mannose receptor
Yin, Zhao-Jun; Li, Qing; Meng, Xiang-Bao; Li, Zhong-Jun
关键词Multivalent Mannoside Mannose Receptor
刊名CARBOHYDRATE RESEARCH
2007-12-28
DOI10.1016/j.carres.2007.08.017
342期:18页:2729-2734
收录类别SCI ; IC
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biochemistry & Molecular Biology ; Chemistry, Applied ; Chemistry, Organic
研究领域[WOS]Biochemistry & Molecular Biology ; Chemistry
关键词[WOS]CARBOHYDRATE-RECOGNITION DOMAINS ; LIGAND-BINDING ; GLYCOSYLATION ; HOMEOSTASIS ; CELLS
英文摘要

According to the characteristics of C-type lectin-like domains in the mannose receptor (MR), a novel design of multivalent mannosides targeting the MR was accomplished. Beginning with a divalent mannoside as the sugar unit, a series of multivalent mannosides with variations in both valence and space were synthesized in a convergent approach. The synthetic multivalent mannosides are to be explored to study MR-sugar binding events. (C) 2007 Elsevier Ltd. All rights reserved.

语种英语
WOS记录号WOS:000251872000004
引用统计
被引频次:7[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/55655
专题北京大学药学院_天然药物与仿生药物国家重点实验室
北京大学药学院_化学生物学系
作者单位Peking Univ, Hlth Sci Ctr, Dept Biol Chem, Sch Pharmaceut Sci,State Key Lab Nat & Biomimet D, Beijing 100083, Peoples R China
推荐引用方式
GB/T 7714
Yin, Zhao-Jun,Li, Qing,Meng, Xiang-Bao,et al. Design and synthesis of novel multivalent mannosides targeting the mannose receptor[J]. CARBOHYDRATE RESEARCH,2007,342(18):2729-2734.
APA Yin, Zhao-Jun,Li, Qing,Meng, Xiang-Bao,&Li, Zhong-Jun.(2007).Design and synthesis of novel multivalent mannosides targeting the mannose receptor.CARBOHYDRATE RESEARCH,342(18),2729-2734.
MLA Yin, Zhao-Jun,et al."Design and synthesis of novel multivalent mannosides targeting the mannose receptor".CARBOHYDRATE RESEARCH 342.18(2007):2729-2734.
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