IR@PKUHSC  > 北京大学第三临床医学院  > 泌尿外科
学科主题临床医学
Automatic segmentation of white matter hyperintensities by an extended FitzHugh & nagumo reaction diffusion model
Ji, Shuangxi1; Ye, Changqing2; Li, Fan2; Sun, Wei2; Zhang, Jue1,3; Huang, Yining2; Fang, Jing1,3
关键词White Matter Hyperintensities Fitzhugh &Amp Nagumo Model Automatic Segmentation Similarity Index
刊名JOURNAL OF MAGNETIC RESONANCE IMAGING
2013-02-01
DOI10.1002/jmri.23836
37期:2页:343-350
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]MULTIPLE-SCLEROSIS LESIONS ; VISUAL RATING-SCALES ; MR-IMAGES ; CARDIOVASCULAR HEALTH ; ALZHEIMERS-DISEASE ; ROTTERDAM SCAN ; OLDER PERSONS ; BRAIN MRI ; QUANTIFICATION ; POPULATION
英文摘要

Purpose: To evaluate the efficiency and reproducibility of the extended Fitz Hugh & Nagumo (FHN) reaction-diffusion model proposed in this study for white matter hyperintensities (WMH) segmentation. Materials and Methods: Five types of magnetic resonance T2-weighted fluid-attenuated inversion-recovery (T2FLAIR) images of 127 patients with different scanning parameters from five clinical scanner systems were selected for this study. After skull and scalp removal and denoise, the T2FLAIR images were processed by the proposed extended FHN model to obtain WMH. This new technique replaced the global threshold constant with a local threshold matrix. Results: There was no significant difference between the segmentation results of the training set and the manual contouring against those between the test set and the manual contouring based on similarity index (SI) values (P = 0.5217). The SI values of the five types of T2FLAIR images were 86.0% +/- 15.4%, 85.8% +/- 10.5%, 84.1% +/- 14.8%, 87.2% +/- 14.6%, 86.3% +/- 12.7%, respectively, comparing the segmentation results using the proposed method to the manual delineations. The overall SI value of the images was 86.5% +/- 14.5%. This approach also demonstrated a better WMH segmentation performance over its classic form (P < 0.001). Conclusion: The proposed approach is efficient and could provide a more effective and convenient tool for clinical quantitative WMH analysis. J. Magn. Reson. Imaging 2013;37:343350. (c) 2012 Wiley Periodicals, Inc.

语种英语
WOS记录号WOS:000314180400007
引用统计
被引频次:3[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/55681
专题北京大学第三临床医学院_泌尿外科
北京大学第一临床医学院_神经内科
作者单位1.Peking Univ, Coll Engn, Beijing 100871, Peoples R China
2.Peking Univ, Hosp 1, Dept Neurol, Beijing 100034, Peoples R China
3.Peking Univ, Acad Adv Interdisciplinary Study, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714
Ji, Shuangxi,Ye, Changqing,Li, Fan,et al. Automatic segmentation of white matter hyperintensities by an extended FitzHugh &amp; nagumo reaction diffusion model[J]. JOURNAL OF MAGNETIC RESONANCE IMAGING,2013,37(2):343-350.
APA Ji, Shuangxi.,Ye, Changqing.,Li, Fan.,Sun, Wei.,Zhang, Jue.,...&Fang, Jing.(2013).Automatic segmentation of white matter hyperintensities by an extended FitzHugh & nagumo reaction diffusion model.JOURNAL OF MAGNETIC RESONANCE IMAGING,37(2),343-350.
MLA Ji, Shuangxi,et al."Automatic segmentation of white matter hyperintensities by an extended FitzHugh & nagumo reaction diffusion model".JOURNAL OF MAGNETIC RESONANCE IMAGING 37.2(2013):343-350.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Ji, Shuangxi]的文章
[Ye, Changqing]的文章
[Li, Fan]的文章
百度学术
百度学术中相似的文章
[Ji, Shuangxi]的文章
[Ye, Changqing]的文章
[Li, Fan]的文章
必应学术
必应学术中相似的文章
[Ji, Shuangxi]的文章
[Ye, Changqing]的文章
[Li, Fan]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。