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学科主题: 临床医学
题名:
Focal atrial tachycardia originating from the left atrial appendage: Electrocardiographic and electrophysiologic characterization and long-term outcomes of radiofrequency ablation
作者: Wang Yun-Long; Li Xue-Bin; Quan Xin; Ma Jin-Xin; Zhang Ping; Xu Yuan; Zhang Hai-Cheng; Guo Ji-Hong
关键词: catheter ablation ; atrial tachycardia ; mapping ; electrocardiography ; supraventricular tachycardia
刊名: JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
发表日期: 2007-05-01
DOI: 10.1111/j.1540-8167.2007.00808.x
卷: 18, 期:5, 页:459-464
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Cardiac & Cardiovascular Systems
研究领域[WOS]: Cardiovascular System & Cardiology
关键词[WOS]: CATHETER ABLATION ; MITRAL ANNULUS ; PREDICT ; SITE
英文摘要:

Introduction: This study sought to investigate electrophysiologic characteristics and radiofrequency ablation (RFA) in patients with focal atrial tachycardia (AT) arising from the left atrial appendage (LAA).

Methods: This study included seven patients undergoing RFA with focal AT. Activation mapping was performed during tachycardia to identify an earlier activation in the left atria and the LAA. The atrial appendage angiography was performed to identify the origin in the LAA before and after RFA.

Results: AT occurred spontaneously or was induced by isoproterenol infusion rather than programmed extrastimulation and burst atrial pacing in any patient. The tachycardia demonstrated a characteristic P-wave morphology and endocardial activation pattern. The P wave was highly positive in inferior leads in all patients. Lead V-1 showed upright or biphasic (+/-) component in all patients. Lead V-2-V-6 showed an isoelectric component in five patients or an upright component with low amplitude (< 0.1 mV) in two patients. Earliest endocardial activity occurred at the distal coronary sinus (CS) ahead of P wave in all seven patients. Mean tachycardia cycle length was 381 +/- 34 msec and the earliest endocardial activation at the successful RFA site occurred 42.3 +/- 9.6 msec before the onset of P wave. RFA was acutely successful in all seven patients. Long-term success was achieved in seven of the seven over a mean follow-up of 24 +/- 5 months.

Conclusions: The LAA is an uncommon site of origin for focal AT (3%). There were consistent P-wave morphology and endocardial activation associated with this type of AT. The LAA focal ablation is safe and effective. Long-term success was achieved with focal ablation in all patients.

语种: 英语
WOS记录号: WOS:000245942200003
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/55721
Appears in Collections:北京大学第二临床医学院_心血管内科_期刊论文

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作者单位: Peking Univ, Peoples Hosp, Dept Cardiol, Beijing 100044, Peoples R China

Recommended Citation:
Wang Yun-Long,Li Xue-Bin,Quan Xin,et al. Focal atrial tachycardia originating from the left atrial appendage: Electrocardiographic and electrophysiologic characterization and long-term outcomes of radiofrequency ablation[J]. JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY,2007,18(5):459-464.
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