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学科主题: 临床医学
题名:
Use of oral anticoagulation among stroke patients with atrial fibrillation in China: the ChinaQUEST (Quality evaluation of stroke care and treatment) registry study
作者: Gao, Qingchun1; Fu, Xian1; Wei, Jade W.2,3; Chen, Xiangyan4; Huang, Yining5; Wang, Jiguang6; Anderson, Craig S.2,3; Wong, Ka Sing4; China QUEST Study Investigators
关键词: atrial fibrillation ; China ; oral anticoagulation ; stroke
刊名: INTERNATIONAL JOURNAL OF STROKE
发表日期: 2013-04-01
DOI: 10.1111/j.1747-4949.2011.00716.x
卷: 8, 期:3, 页:150-154
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Peripheral Vascular Disease
研究领域[WOS]: Cardiovascular System & Cardiology
关键词[WOS]: RISK ; WARFARIN ; POPULATION ; PREVENTION ; MANAGEMENT ; THERAPY
英文摘要:

Background International guidelines recommend oral anticoagulation in patients with atrial fibrillation according to their level of stroke risk. This study aimed to determine oral anticoagulation use in atrial fibrillation patients with recent ischemic stroke and examine factors that impact such management in China. Methods Among the patients with acute ischemic stroke (n=4782) from the China QUality Evaluation of Stroke Care and Treatment study, a multicenter, prospective, 62-hospital registry in China, there were 499 (10%) (mean age 70 +/- 12years, 49% female) with documented atrial fibrillation with outcome data over 12months of follow-up. Logistic regression analysis was used to identify the independent predictors of oral anticoagulation use in these patients. Results Of the 499 stroke patients with atrial fibrillation, oral anticoagulation use was 20% overall but varied from 8% prestroke and 11% in-hospital (poststroke), to 13% and 10% at three-months and 12months, respectively. Oral anticoagulation use was independently associated with younger age (odds ratio 0 center dot 95, 95% confidence interval 0 center dot 930 center dot 97, P<0 center dot 001), nonmanual occupation (odds ratio 0 center dot 44, 95% confidence interval 0 center dot 250 center dot 80, P=0 center dot 006), and less cardiovascular risk factors (odds ratio 0 center dot 81, 95% confidence interval 0 center dot 680 center dot 96, P=0 center dot 02). Conclusions These data indicate oral anticoagulation use is lower in stroke patients with atrial fibrillation in China than that in Western countries, being applied more often in those of younger age, nonmanual occupation, and having less cardiovascular risk factors.

语种: 英语
WOS记录号: WOS:000316327800008
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/55773
Appears in Collections:北京大学第一临床医学院_神经内科_期刊论文

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作者单位: 1.Univ Sydney, Sydney, NSW 2006, Australia
2.Guangzhou Med Univ, Affiliated Hosp 2, Inst Neurosci, Guangzhou, Guangdong, Peoples R China
3.Royal Prince Alfred Hosp, George Inst Global Hlth, Sydney, NSW, Australia
4.Chinese Univ Hong Kong, Prince Wales Hosp, Dept Med & Therapeut, Hong Kong 999077, Hong Kong, Peoples R China
5.Peking Univ, Hosp 1, Dept Neurol, Beijing 100871, Peoples R China
6.Shanghai Jiao Tong Univ, Sch Med, Ctr Epidemiol Studies & Clin Trials, Shanghai Inst Hypertens,Ruijin Hosp & Hosp, Shanghai 200030, Peoples R China

Recommended Citation:
Gao, Qingchun,Fu, Xian,Wei, Jade W.,et al. Use of oral anticoagulation among stroke patients with atrial fibrillation in China: the ChinaQUEST (Quality evaluation of stroke care and treatment) registry study[J]. INTERNATIONAL JOURNAL OF STROKE,2013,8(3):150-154.
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