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学科主题基础医学
Serum erythropoietin: a useful biomarker for coronary collateral development and potential target for therapeutic angiogenesis among the patients with coronary chronic total occlusion
Xu, Weixian; Guo, Zhiguo; Mi, Lin; Wang, Guisong
关键词Chronic Total Occlusions Coronary Artery Disease Coronary Collateral Development Erythropoietin Vascular Endothelial Growth Factor
刊名BIOMARKERS
2013-06-01
DOI10.3109/1354750X.2013.787459
18期:4页:343-348
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biotechnology & Applied Microbiology ; Toxicology
资助者Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; National Natural Science Foundation of China ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; National Natural Science Foundation of China
研究领域[WOS]Biotechnology & Applied Microbiology ; Toxicology
关键词[WOS]ACUTE MYOCARDIAL-INFARCTION ; ENDOTHELIAL GROWTH-FACTOR ; CARDIAC-FUNCTION ; TRIAL ; INTERVENTION ; ISCHEMIA ; PORCINE ; LEVEL ; PILOT
英文摘要

The study was to investigate the association of endogenous erythropoietin (EPO) and coronary collateral development. Forty-nine patients (31 with chronic total occlusion (CTO), 18 with normal coronary artery) were consecutively enrolled. The serum EPO was positively related with Rentrop class. Increased serum EPO was one of the independent predictors of good collateral development (odds ratio 1.31; p = 0.025). A significantly positive correlation was seen between serum EPO and vascular endothelial growth factor (VEGF) levels (r = 0.96, p < 0.001). Circulatory EPO may be a useful biomarker for coronary collateral development and potential target for therapeutic angiogenesis in patients with CTO.

语种英语
所属项目编号81170179
资助者Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; National Natural Science Foundation of China ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; National Natural Science Foundation of China
WOS记录号WOS:000319525700009
引用统计
被引频次:9[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/55814
专题北京大学基础医学院_心血管所
作者单位Peking Univ, Key Lab Cardiovasc Mol Biol & Regulatory Peptides, Key Lab Mol Cardiovasc Sci, Dept Cardiol,Hosp 3,Minist Hlth,Minist Educ, Beijing 100191, Peoples R China
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GB/T 7714
Xu, Weixian,Guo, Zhiguo,Mi, Lin,et al. Serum erythropoietin: a useful biomarker for coronary collateral development and potential target for therapeutic angiogenesis among the patients with coronary chronic total occlusion[J]. BIOMARKERS,2013,18(4):343-348.
APA Xu, Weixian,Guo, Zhiguo,Mi, Lin,&Wang, Guisong.(2013).Serum erythropoietin: a useful biomarker for coronary collateral development and potential target for therapeutic angiogenesis among the patients with coronary chronic total occlusion.BIOMARKERS,18(4),343-348.
MLA Xu, Weixian,et al."Serum erythropoietin: a useful biomarker for coronary collateral development and potential target for therapeutic angiogenesis among the patients with coronary chronic total occlusion".BIOMARKERS 18.4(2013):343-348.
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