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学科主题: 公共卫生
题名:
Protective Effect of Corn Oligopeptides on Acute Alcoholism in Rodent Models
作者: Zhang, Feng1,2; Zhang, Jiali1,2; Xu, Meihong1,2; Dai, Xiaoqian1,2; Li, Yujie1,2; Ding, Ye1,2; Zhang, Zhaofeng1,2; Li, Yong1,2
关键词: Acute alcoholism ; corn oligopeptides ; ethanol ; protective effect ; control group
刊名: JOURNAL OF ANIMAL AND VETERINARY ADVANCES
发表日期: 2012
卷: 11, 期:12, 页:2070-2074
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Veterinary Sciences
研究领域[WOS]: Veterinary Sciences
关键词[WOS]: GLUTEN MEAL ; METABOLISM ; PEPTIDE
英文摘要:

The present study aimed to investigate the effects of Corn Oligopeptides (COP) on acute alcoholism in rat models. Female SD rats were randomly assigned to 4 groups per test including control group and 3 COP intervention groups (2.25, 4.5 and 9 g/kg/BW). About 5 g/kg/BW ethanol (8 g/kg/BW for loss of righting reflex test) was given intragastricly 10 min before COP treatment. Ethanol levels in blood, behavioral studies and ADH activity in liver were assayed. Researchers found that COP treatment could promote the alcohol metabolism and correct the movement disorder caused by alcohol consumption to some extent. However, the ADH levels had no changes among different groups. These findings suggest that COP have a protective effect on acute alcoholism in rats.

语种: 英语
所属项目编号: 2006BAD27B08
项目资助者: Foundation from the Ministry of Science and Technology of the People&prime ; s Republic of China
WOS记录号: WOS:000306475500019
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/55837
Appears in Collections:北京大学公共卫生学院_期刊论文

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作者单位: 1.Peking Univ, Sch Publ Hlth, Dept Nutr & Food Hyg, Beijing 100191, Peoples R China
2.Peking Univ, Beijing Key Lab Toxicol Res & Risk Assessment Foo, Beijing 100191, Peoples R China

Recommended Citation:
Zhang, Feng,Zhang, Jiali,Xu, Meihong,et al. Protective Effect of Corn Oligopeptides on Acute Alcoholism in Rodent Models[J]. JOURNAL OF ANIMAL AND VETERINARY ADVANCES,2012,11(12):2070-2074.
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