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学科主题: 临床医学
题名:
Subtraction Elastography for the Evaluation of Ablation-induced Lesions: A Feasibility Study
作者: Shao, Jinhua; Wang, Jinrui; Zhang, Yizhuo; Cui, Ligang; Liu, Ke; Bai, Jing
刊名: IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL
发表日期: 2009
DOI: 10.1109/TUFFC.2009.1004
卷: 56, 期:1, 页:44-54
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Acoustics ; Engineering, Electrical & Electronic
研究领域[WOS]: Acoustics ; Engineering
关键词[WOS]: ACOUSTIC RADIATION FORCE ; INDUCED HEPATIC-LESIONS ; IN-VIVO ; THERMAL LESIONS ; TRANSIENT ELASTOGRAPHY ; ULTRASOUND ELASTOGRAPHY ; RADIOFREQUENCY ABLATION ; IMAGE REGISTRATION ; FOCUSED ULTRASOUND ; LOWER-EXTREMITY
英文摘要:

Different noninvasive or minimally invasive therapeutic ablation procedures can produce tissue necrosis associated with local-stiffness increase. Although elastography has been proved as a potential evaluation tool for many kinds of ablation-induced lesions, the application of subtraction technique in elastography to enhance the visualization of the ablation lesions has rarely been reported. In this paper, subtraction elastography is proposed to evaluate the ablation-induced lesions. Three models are constructed to simulate different kinds of ablated inclusions. The simulation results showed that subtraction elastography is superior to conventional elastography in detecting the ablation-induced lesions with higher signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR). The artifacts induced by elastographic signal processing algorithms can be largely reduced in subtraction elastography. In addition, subtraction elastography is less influenced by the stiff background and can provide more reliable boundary information about the lesion than conventional elastography. Furthermore, the feasibility Of Subtraction elastography is validated by an in vitro experiment of ethanol-induced hepatic lesions. The preliminary results of this work suggest that subtraction elastography may be a good option for the evaluation of ablation-induced lesions.

语种: 英语
所属项目编号: 30470466 ; 30670577 ; 60571013 ; 60331010
项目资助者: National Natural Science Foundation of China ; Tsinghua-Yue-Yuan Medical Science Foundation ; National Basic Research Program of China ; Special Research Fund for Doctoral Program of Higher Education of China
WOS记录号: WOS:000262561600007
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/55928
Appears in Collections:北京大学第三临床医学院_期刊论文

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作者单位: Peking Univ, Hosp 3, Dept Diagnost Ultrasound, Beijing 100871, Peoples R China

Recommended Citation:
Shao, Jinhua,Wang, Jinrui,Zhang, Yizhuo,et al. Subtraction Elastography for the Evaluation of Ablation-induced Lesions: A Feasibility Study[J]. IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL,2009,56(1):44-54.
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