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学科主题: 精神卫生
题名:
The cognitive subscale of Alzheimer′s disease assessment scale, Chinese version in staging of Alzheimer disease
作者: Wang, H; Yu, X; Li, SR; Chen, YF; Li, HD; He, J
关键词: Alzheimer&prime ; s disease Assessment Scale (ADAS) ; cognitive impairment ; dementia staging ; Chinese
刊名: ALZHEIMER DISEASE & ASSOCIATED DISORDERS
发表日期: 2004-10-01
卷: 18, 期:4, 页:231-235
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Clinical Neurology ; Pathology
研究领域[WOS]: Neurosciences & Neurology ; Pathology
关键词[WOS]: ADAS ; PERFORMANCE ; EDUCATION ; DEMENTIA ; PATTERNS ; TRIALS
英文摘要:

This study was designed to examine the utility of the ADAS-Cog, Chinese version (ADAS-Cog-C) for staging of dementia in Alzheimer disease (AD). A total of 305 patients with AD (199 mild AD and 106 moderate AD) meeting the NINCDS-ADRDA criteria of probable AD were recruited. The ADAS-Cog-C was administered to all AD subjects. The total score of ADAS-Cog-C and each item score differed significantly between mild and moderate AD groups, with moderate AD group scoring higher. Statistical analysis showed insignificant influence of age or educational level on the ADAS-Cog-C total score. The item score of orientation and constructional praxis and the ADAS-Cog total score could classify mild and moderate AD efficiently, with a sensitivity of 78% to 82% and a specificity of 70% to 73%. The results of this study indicate that the ADAS-Cog-C can discriminate mild AD from moderate AD efficiently and be useful for staging of AD. It is recommended that the ADAS-Cog-C be introduced for monitoring the cognitive efficacy in AD drug treatment among Chinese AD patients.

语种: 英语
WOS记录号: WOS:000225930000014
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/55986
Appears in Collections:北京大学精神卫生研究所_期刊论文

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作者单位: 1.Peking Univ, Inst Mental Hlth, Dept Geriatr Psychiat, Beijing 100871, Peoples R China
2.Peking Univ, Inst Mental Hlth, Dept Social Psychiat & Behav Med, Beijing 100871, Peoples R China
3.Peking Univ, Inst Mental Hlth, Dept Psychiat, Beijing 100871, Peoples R China

Recommended Citation:
Wang, H,Yu, X,Li, SR,et al. The cognitive subscale of Alzheimer′s disease assessment scale, Chinese version in staging of Alzheimer disease[J]. ALZHEIMER DISEASE & ASSOCIATED DISORDERS,2004,18(4):231-235.
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