IR@PKUHSC  > 北京大学第三临床医学院  > 骨科
学科主题临床医学
Predicting the need for blood transfusions in elderly patients with pertrochanteric femoral fractures
Hou, Guojin; Zhou, Fang; Tian, Yun; Ji, Hongquan; Zhang, Zhishan; Guo, Yan; Lv, Yang
关键词Blood Transfusion Allogeneic Hip Fractures Pertrochanteric Fractures Surgery Internal Fixation Perioperative Period The Elderly
刊名INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
2014-12-01
DOI10.1016/j.injury.2014.08.033
45期:12页:1932-1937
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Critical Care Medicine ; Emergency Medicine ; Orthopedics ; Surgery
研究领域[WOS]General & Internal Medicine ; Emergency Medicine ; Orthopedics ; Surgery
关键词[WOS]HIP FRACTURE ; SURGERY ; NECK ; REQUIREMENTS ; INFECTION ; TRIGGERS ; REPAIR ; ANEMIA ; FEMUR ; RISK
英文摘要

Objective: The need exists for perioperative blood management measures aimed at improving patient outcomes and reducing the risks of allogeneic blood transfusion (ABT). Our study aim is to discuss an algorithm to predict the need for perioperative blood transfusion in old patients with pertrochanteric femoral fractures.

Methods: We retrospectively analysed the data from 220 elderly patients with pertrochanteric femoral fractures with regard to the probability of receiving an ABT within 72 h after surgery. The patients were divided into ABT and non-ABT groups. A univariate analysis was used to compare between-group differences with regard to 13 variables. A logistic regression analysis and a probability algorithm to predict the need for an ABT based on independent predictors were used.

Results: The non-ABT group included 131 patients (55 males and 76 females), with an average age of 77.2 +/- 6.8 years; the ABT group included 89 patients (29 males and 60 females), with an average age of 79.7 +/- 6.6 years. The total volume of transfused blood was 276 Units; the actual average blood transfusion was 3.1 +/- 1.47 Units. Significant between-group differences (P < 0.05) were observed with regard to age, duration of operation, haemoglobin (Hb) at admission, intra-operative blood loss, type of fracture and type of anaesthesia. The mean volume of transfused blood in the proximal femoral nail anti-rotation (PFNA) and Gamma3 group was larger than that of the dynamic hip screw (DHS) group (P < 0.05). A logistic regression analysis revealed that patients with pertrochanteric femoral fractures who were elderly (> 81 years), had lower Hb levels at admission (<= 124 g/L), longer duration of operations (t > 85 min), underwent intramedullary fixation (Gamma3 and PFNA) and had more intra-operative blood loss were more likely to need an ABT. This regression model predicted 74.1% of the transfused cases.

Conclusions: An algorithm was devised to predict and manage the need for an ABT within 72 h after surgery in patients with pertrochanteric femoral fractures. A reasonable transfusion program might reduce the complications caused by anaemia and effectively avoid the risks associated with ABTs. (C) 2014 Elsevier Ltd. All rights reserved.

语种英语
WOS记录号WOS:000348652100020
Citation statistics
Cited Times:8[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/56003
Collection北京大学第三临床医学院_骨科
作者单位Peking Univ, Hosp 3, Dept Orthopaed Surg, Beijing 100191, Peoples R China
Recommended Citation
GB/T 7714
Hou, Guojin,Zhou, Fang,Tian, Yun,et al. Predicting the need for blood transfusions in elderly patients with pertrochanteric femoral fractures[J]. INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED,2014,45(12):1932-1937.
APA Hou, Guojin.,Zhou, Fang.,Tian, Yun.,Ji, Hongquan.,Zhang, Zhishan.,...&Lv, Yang.(2014).Predicting the need for blood transfusions in elderly patients with pertrochanteric femoral fractures.INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED,45(12),1932-1937.
MLA Hou, Guojin,et al."Predicting the need for blood transfusions in elderly patients with pertrochanteric femoral fractures".INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED 45.12(2014):1932-1937.
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