北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第一临床医学院  > 期刊论文
学科主题: 临床医学
题名:
Performance of the American College of Rheumatology/European League Against Rheumatism 2010 criteria for the diagnosis of rheumatoid arthritis in Chinese patients
作者: Zhao, Juan; Li, Guangtao; Xu, Jing; Zhang, Xiaohui; Zhang, Zhuoli
关键词: Rheumatoid arthritis ; Classification criteria ; Sensitivity ; Specificity
刊名: JOINT BONE SPINE
发表日期: 2013-10-01
DOI: 10.1016/j.jbspin.2013.11.006
卷: 80, 期:5, 页:482-487
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Rheumatology
研究领域[WOS]: Rheumatology
关键词[WOS]: 1987 ACR CRITERIA ; CLASSIFICATION CRITERIA ; INFLAMMATORY POLYARTHRITIS ; METHODOLOGICAL REPORT ; ANTIBODIES ; SPECIFICITY ; SENSITIVITY ; DURATION ; COHORTS
英文摘要:

Objectives: To evaluate the ability of American College of Rheumatology (ACR) 2010 classification criteria to diagnose rheumatoid arthritis (RA) compared to the widely used ACR 1987 criteria in Chinese patients.

Methods: Four hundred and four patients suffering from arthritis were included in the study. Two hundred and twenty-one of them were classified as RA patients and 183 had alternative diagnoses. The patients were further subdivided into three groups according to their disease duration of within one year, one to two years or more than two years. The diagnostic value of ACR/EULAR 2010 criteria for RA was evaluated by comparing the sensitivity and specificity with those of ACR 1987 criteria in these patients.

Results: The sensitivity and specificity of ACR/EULAR 2010 criteria for diagnosing RA were 95% and 92.9%, respectively. In contrast, the sensitivity and specificity of ACR 1987 criteria were 81.4% and 92.9%, respectively. The efficacy of ACR/EULAR 2010 criteria was superior to the ACR 1987 criteria by comparing their area under the curves (AUC) (0.940, 95% CI [0.912, 0.967] vs. 0.872, 95% CI [0.835, 0.909]). The recognition accuracy of ACR/EULAR 2010 criteria was higher than that of ACR 1987 criteria (94.5% vs. 86.6%, < 0.05). Inter-rater analysis showed that agreement of the two criteria was substantial (Kappa = 0.744, 13< 0.001). For patients with disease duration within one year, one to two years and over two years, the sensitivities of ACR 1987 criteria were 69.2%, 81.3% and 89.9%, while the specificities were 94.4%, 90.6% and 92%, respectively. The corresponding sensitivities of ACR/EULAR 2010 criteria in these patients were 91%, 93.8% and 98.2%, while the corresponding specificities were 94.4%, 96.6% and 89.3%, respectively. The advantage of ACR/EULAR 2010 criteria over 1987 criteria in higher sensitivity was remarkable particularly in patients with disease duration within one year (P< 0.001).

Conclusions: The ACR/EULAR 2010 criteria is more accurate in RA diagnosis compared to the ACR 1987 criteria by elevating the sensitivity while preserving the specificity, especially in patients with disease duration within one year. The ACR/EULAR 2010 criteria may serve as new diagnostic tools in daily clinical practice. (C) 2012 Societe francaise de rhumatologie. Published by Elsevier Masson SAS. All rights reserved.

语种: 英语
所属项目编号: 2010CB529103 ; Z080507030808022
项目资助者: "973" Sub-topics Science and the Technology ; Beijing Municipal Science and Technology Commission - funded projects
WOS记录号: WOS:000326683200009
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/56056
Appears in Collections:北京大学第一临床医学院_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: Peking Univ, Hosp 1, Dept Rheumatol & Clin Immunol, Beijing 100034, Peoples R China

Recommended Citation:
Zhao, Juan,Li, Guangtao,Xu, Jing,et al. Performance of the American College of Rheumatology/European League Against Rheumatism 2010 criteria for the diagnosis of rheumatoid arthritis in Chinese patients[J]. JOINT BONE SPINE,2013,80(5):482-487.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Zhao, Juan]'s Articles
[Li, Guangtao]'s Articles
[Xu, Jing]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Zhao, Juan]‘s Articles
[Li, Guangtao]‘s Articles
[Xu, Jing]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace