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学科主题临床医学
Endoprosthetic replacement for primary tumours around the knee - Experience from Peking University
Guo, W.; Ji, T.; Yang, R.; Tang, X.; Yang, Y.
刊名JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME
2008-08-01
DOI10.1302/0301-620X.90B8.20240
90B期:8页:1084-1089
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Orthopedics ; Surgery
研究领域[WOS]Orthopedics ; Surgery
关键词[WOS]DISTAL FEMUR ; BONE-TUMORS ; MALIGNANT-TUMORS ; PROXIMAL TIBIA ; FUNCTIONAL-EVALUATION ; MODULAR FEMUR ; LIMB SALVAGE ; FOLLOW-UP ; RECONSTRUCTION ; RESECTION
英文摘要

In developing countries locally-made low-cost prostheses are mainly used in limb-salvage surgery to alleviate the economic burden.

We retrospectively collected data on 104 patients treated by limb-salvage surgery between July 1997 and July 2005. We used a locally-designed and fabricated stainless-steel endoprosthesis in each case. Oncological and functional outcomes were evaluated at a mean follow-up of 47 months (12 to 118).

A total of 73 patients (70.2%) were free from disease, nine (8.7%) were alive with disease, 19 (18.2%) had died from their disease and three (2.9%) from unrelated causes. According to the Musculoskeletal Tumor Society scoring system, the mean functional score was 76.3% (SD 17.8). The five-year survival for the implant was 70.5%. There were nine cases ( 8.7%) of infection, seven early and two late, seven (6.7%) of breakage of the prosthesis, three ( 2.9%) of aseptic loosening and two (1.9%) of failure of the polyethylene bushing. Multivariate analysis showed that a proximal tibial prosthesis and a resection length of 14 cm or more were significant negative prognostic factors.

Our survival rates and Musculoskeletal Tumor Society functional scores are similar to those reported in the literature. Although longer follow-up is needed to confirm our results, we believe that a low-cost custom-made endoprosthesis is a cost-effective and reliable reconstructive option for limb salvage in developing countries.

语种英语
WOS记录号WOS:000258098000019
引用统计
被引频次:29[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/56066
专题北京大学第二临床医学院_骨肿瘤科
作者单位Peking Univ, Musculoskeletal Tumor Ctr, Peoples Hosp, Beijing 100044, Peoples R China
推荐引用方式
GB/T 7714
Guo, W.,Ji, T.,Yang, R.,et al. Endoprosthetic replacement for primary tumours around the knee - Experience from Peking University[J]. JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME,2008,90B(8):1084-1089.
APA Guo, W.,Ji, T.,Yang, R.,Tang, X.,&Yang, Y..(2008).Endoprosthetic replacement for primary tumours around the knee - Experience from Peking University.JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME,90B(8),1084-1089.
MLA Guo, W.,et al."Endoprosthetic replacement for primary tumours around the knee - Experience from Peking University".JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME 90B.8(2008):1084-1089.
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