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Russell body gastritis/duodenitis: A case series and description of immunoglobulin light chain restriction
Zhang, Hejun; Jin, Zhu; Cui, Rongli
刊名CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY
2014-10-01
DOI10.1016/j.clinre.2014.05.008
38期:5页:E89-E97
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Gastroenterology & Hepatology
研究领域[WOS]Gastroenterology & Hepatology
关键词[WOS]HELICOBACTER-PYLORI INFECTION ; GASTRITIS CASE-REPORT ; HIV-POSITIVE PATIENT ; OF-THE-LITERATURE ; PLASMA-CELLS ; BODIES ; MONOCLONALITY ; STOMACH ; MUCOSA ; TUMOR
英文摘要

Russell body esophago-gastro-duodenitis is an unusual form of chronic inflammation, with only 22 cases being reported in PubMed. However, the prevalence and clinical significance remain unknown. This report describes the clinico-pathological characteristics of nine cases of Russell body gastritis (RBG) and one case of Russell body duodentitis (RBD), with nonspecific endoscopic appearance. The Mott cells (plasma cells with Russell bodies) showed kappa light chain restriction in eight gastritis cases and lambda light chain restriction in the duodentitis case, and there were no histological features that suggested lymphoma. Thus, a diagnosis of monoclonal RBG/RBD was made. Helicobacter pylori infection was found in 55.6% of RBG cases and in the RBD case. And, the clinical follow-up evaluations were uneventful. This report is the first study to describe this benign disease entity with monoclonality on a large-scale basis. In addition, the monoclonality of Mott cells cannot be used as evidence of an existing neoplastic lesion, and taken together, these findings may indicate a reactive process. (C) 2014 Elsevier Masson SAS. All rights reserved.

语种英语
WOS记录号WOS:000345502400001
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被引频次:8[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/56068
专题北京大学第三临床医学院_消化科
作者单位Peking Univ Third Hosp, Dept Gastroenterol, Pathol Lab, Beijing 100191, Peoples R China
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GB/T 7714
Zhang, Hejun,Jin, Zhu,Cui, Rongli. Russell body gastritis/duodenitis: A case series and description of immunoglobulin light chain restriction[J]. CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY,2014,38(5):E89-E97.
APA Zhang, Hejun,Jin, Zhu,&Cui, Rongli.(2014).Russell body gastritis/duodenitis: A case series and description of immunoglobulin light chain restriction.CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY,38(5),E89-E97.
MLA Zhang, Hejun,et al."Russell body gastritis/duodenitis: A case series and description of immunoglobulin light chain restriction".CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY 38.5(2014):E89-E97.
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