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学科主题: 药学
题名:
Characteristic fragmentation behavior of phosphoamino acid conjugates with 3 ′-azido-3 ′-deoxythymidine by electrospray ionization tandem mass spectrometry
作者: Xiao, Q; Ju, Y; Zhao, YF; Cui, YX
刊名: RAPID COMMUNICATIONS IN MASS SPECTROMETRY
发表日期: 2003
DOI: 10.1002/rcm.1186
卷: 17, 期:20, 页:2273-2278
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Analytical ; Spectroscopy
研究领域[WOS]: Chemistry ; Spectroscopy
关键词[WOS]: H-PHOSPHONATES ; AMINO-ACIDS ; AZT ; DERIVATIVES ; PRODRUGS
英文摘要:

The conjugates of phosphoamino acids with 3′-azido-3′-deoxythymidine were synthesized and their structures were determined by various spectral methods. In positive and negative ion electrospray mass spectrometry (ESI-MS), the fragmentation pathways were investigated in conjunction with tandem mass spectrometry (MS/MS). The results showed that there were very different characteristic fragment ions in the positive ion MS/MS spectra and the negative ion MS/MS spectra. Copyright (C) 2003 John Wiley Sons, Ltd.

语种: 英语
WOS记录号: WOS:000185867500005
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/56081
Appears in Collections:北京大学药学院_期刊论文

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作者单位: 1.Tsing Hua Univ, Minist Educ, Key Lab Bioorgan Phosphorus Chem, Dept Chem, Beijing 100084, Peoples R China
2.Peking Univ, Sch Pharmaceut Sci, Natl Res Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China

Recommended Citation:
Xiao, Q,Ju, Y,Zhao, YF,et al. Characteristic fragmentation behavior of phosphoamino acid conjugates with 3 ′-azido-3 ′-deoxythymidine by electrospray ionization tandem mass spectrometry[J]. RAPID COMMUNICATIONS IN MASS SPECTROMETRY,2003,17(20):2273-2278.
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