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Tc-99m(V)-dimercaptosuccinic acid scintigraphy in detecting neck metastases in oral squamous cell carcinoma with clinically negative necks
Zhang, Ye1; Guo, Chuanbin1; Yu, Guangyan1; Zhang, Chunli2
关键词Radioautography Dimercaptosuccinic Acid Technetium Squamous Cell Carcinoma Lymph Node
刊名ORAL ONCOLOGY
2009-06-01
DOI10.1016/j.oraloncology.2008.06.008
45期:6页:492-495
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Oncology ; Dentistry, Oral Surgery & Medicine
研究领域[WOS]Oncology ; Dentistry, Oral Surgery & Medicine
关键词[WOS]SENTINEL NODE CONCEPT ; CANCER ; HEAD ; CAVITY ; DISSECTION ; BIOPSY ; MANAGEMENT ; MOUTH ; FLOOR
英文摘要

This study compares the accuracy of Tc-99m(V)-dimercaptosuccinic acid (Tc-99m(V)-DMSA) Single Photon Emission Computer Tomography (SPECT) by intravenous or local injection in the detection of occult cervical lymph node metastases in clinically N0 squamous cell carcinoma of the oral cavity. Fifty-eight previously untreated patients without clinically detectable cervical metastases were included in the study and were divided into two groups. Twenty-eight patients were in the intravenous injection group and 30 patients were in the local injection (around primary tumors) group. Both groups received Tc-99m(V)DMSA, and Tc-99m(V)-DMSA SPECT was performed on all patients. All isolated lymph nodes in neck dissection specimens were stained using H & E. The sensitivity, specificity, and accuracy for intravenous injection of Tc-99m(V)-DMSA was 62.5%, 95.0%, and 85.7%, respective, and 84.6%, 82.4%, and 83.3%, respectively, for local injection. SPECT scan of Tc-99m(V)-DMSA injected around the tumor is a simple and efficient approach to detecting metastatic lymph nodes in clinically N0 patients with oral cancer. (C) 2008 Elsevier Ltd. All rights reserved.

语种英语
WOS记录号WOS:000266271100010
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/56148
专题北京大学第一临床医学院
北京大学口腔医学院_外科
作者单位1.Peking Univ, Sch & Hosp Stomatol, Dept Oral & Maxillofacial Surg, Beijing 100871, Peoples R China
2.Peking Univ, Hosp 1, Beijing 100871, Peoples R China
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Zhang, Ye,Guo, Chuanbin,Yu, Guangyan,et al. Tc-99m(V)-dimercaptosuccinic acid scintigraphy in detecting neck metastases in oral squamous cell carcinoma with clinically negative necks[J]. ORAL ONCOLOGY,2009,45(6):492-495.
APA Zhang, Ye,Guo, Chuanbin,Yu, Guangyan,&Zhang, Chunli.(2009).Tc-99m(V)-dimercaptosuccinic acid scintigraphy in detecting neck metastases in oral squamous cell carcinoma with clinically negative necks.ORAL ONCOLOGY,45(6),492-495.
MLA Zhang, Ye,et al."Tc-99m(V)-dimercaptosuccinic acid scintigraphy in detecting neck metastases in oral squamous cell carcinoma with clinically negative necks".ORAL ONCOLOGY 45.6(2009):492-495.
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