IR@PKUHSC  > 北京大学基础医学院  > 生物物理学系
学科主题基础医学
Investigation of hepatic fibrosis in rats with x-ray diffraction enhanced imaging
Li, Hui1,2; Zhang, Lu1; Wang, Xueyan1; Wang, Tailing3; Wang, Baoen4; Zhao, Xinyan4; Luo, Shuqian1
关键词biological tissues diagnostic radiography image enhancement liver medical image processing X-ray diffraction
刊名APPLIED PHYSICS LETTERS
2009-03-23
DOI10.1063/1.3104860
94期:12
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Physics, Applied
研究领域[WOS]Physics
关键词[WOS]LIVER FIBROSIS
英文摘要

X-ray diffraction enhanced imaging (DEI) is a phase contrast technique that generates excellent contrast of biological soft tissues compared to conventional absorption radiography. We explore the application of DEI in the diagnosis of hepatic fibrosis. The produced refraction contrast images of fibrous rat liver samples show clearly abnormal liver architectures. Moreover, by comparing to histological pictures, different stages of fibrosis are discriminated, and the corresponding morphological features are analyzed. Besides, quantitative analyses of texture features are presented. The results reported herein show that DEI can be a potential noninvasive technique to diagnose and stage hepatic fibrosis.

语种英语
WOS记录号WOS:000264633500078
项目编号60532090 ; 30770593
资助机构National Natural Science Foundation of China
引用统计
被引频次:3[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
版本出版稿
条目标识符http://ir.bjmu.edu.cn/handle/400002259/56160
专题北京大学基础医学院_生物物理学系
作者单位1.Capital Med Univ, Sch Biomed Engn, Beijing 100069, Peoples R China
2.Peking Univ, Hlth Sci Ctr, Dept Med Phys, Beijing 100191, Peoples R China
3.China Japan Friendship Hosp, Dept Pathol, Beijing 100029, Peoples R China
4.Beijing Friendship Hosp, Liver Res Ctr, Beijing 100050, Peoples R China
推荐引用方式
GB/T 7714
Li, Hui,Zhang, Lu,Wang, Xueyan,et al. Investigation of hepatic fibrosis in rats with x-ray diffraction enhanced imaging[J]. APPLIED PHYSICS LETTERS,2009,94(12).
APA Li, Hui.,Zhang, Lu.,Wang, Xueyan.,Wang, Tailing.,Wang, Baoen.,...&Luo, Shuqian.(2009).Investigation of hepatic fibrosis in rats with x-ray diffraction enhanced imaging.APPLIED PHYSICS LETTERS,94(12).
MLA Li, Hui,et al."Investigation of hepatic fibrosis in rats with x-ray diffraction enhanced imaging".APPLIED PHYSICS LETTERS 94.12(2009).
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