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Prevalence and risk factors for esophageal squamous cell cancer and precursor lesions in Anyang, China: a population-based endoscopic survey
He, Z.; Zhao, Y.; Guo, C.; Liu, Y.; Sun, M.; Liu, F.; Wang, X.; Guo, F.; Chen, K.; Gao, L.; Ning, T.; Pan, Y.; Li, Y.; Zhang, S.; Lu, C.; Wang, Z.; Cai, H.; Ke, Y.
关键词Prevalence Risk Factor Esophageal Cancer Precursor Lesion China
刊名BRITISH JOURNAL OF CANCER
2010-09-28
DOI10.1038/sj.bjc.6605843
103期:7页:1085-1088
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Oncology
研究领域[WOS]Oncology
关键词[WOS]NUTRITION INTERVENTION TRIAL ; REPUBLIC-OF-CHINA ; GASTRIC CANCERS ; INCIDENT ESOPHAGEAL ; TOOTH LOSS ; FOLLOW-UP ; LINXIAN ; CARCINOMA ; COHORT
英文摘要

BACKGROUND: The etiology of esophageal squamous cell cancer (ESCC) in high prevalence regions of China remains unclear.

METHODS: Endoscopic biopsies were conducted among 7381 inhabitants aged from 25 to 65 of Anyang, China.

RESULTS: In this study, 2.57, 0.20 and 0.16% of the participants had mild, moderate and severe squamous dysplasia, respectively; 0.19 and 0.08% showed squamous carcinoma in situ and invasive ESCC. Using deep well (depth >100 meters) as water source (odds ratio = 0.72, 95% confidence interval: 0.54-0.96) was negatively associated with ESCC and its precursors, whereas tobacco and alcohol use were not significantly associated with ESCC.

CONCLUSIONS: Water source and other factors in this region need further evaluation by longitudinal studies. British Journal of Cancer (2010) 103, 1085-1088. doi:10.1038/sj.bjc.6605843 www.bjcancer.com Published online 10 August 2010 (C) 2010 Cancer Research UK

语种英语
WOS记录号WOS:000282222000021
项目编号30430710 ; 30930102 ; 2006AA2Z467 ; 2006AA02A403 ; 200902002-8 ; 7100001 ; Z09050703080902
资助机构Natural Science Foundation of China ; National Ministry of Science and Technology ; Public Welfare Industry of Health ; Natural Science Foundation of Beijing ; Beijing Project on Science and Technology Commission
引用统计
被引频次:27[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/56179
专题北京大学临床肿瘤学院
北京大学基础医学院
北京大学第三临床医学院_骨科
北京大学临床肿瘤学院_病理科
北京大学临床肿瘤学院_遗传学研究室
作者单位Peking Univ, Sch Oncol, Beijing Canc Hosp & Inst,Lab Genet, Key Lab Carcinogenesis & Translat Res Minist Educ, Beijing 100142, Peoples R China
推荐引用方式
GB/T 7714
He, Z.,Zhao, Y.,Guo, C.,et al. Prevalence and risk factors for esophageal squamous cell cancer and precursor lesions in Anyang, China: a population-based endoscopic survey[J]. BRITISH JOURNAL OF CANCER,2010,103(7):1085-1088.
APA He, Z..,Zhao, Y..,Guo, C..,Liu, Y..,Sun, M..,...&Ke, Y..(2010).Prevalence and risk factors for esophageal squamous cell cancer and precursor lesions in Anyang, China: a population-based endoscopic survey.BRITISH JOURNAL OF CANCER,103(7),1085-1088.
MLA He, Z.,et al."Prevalence and risk factors for esophageal squamous cell cancer and precursor lesions in Anyang, China: a population-based endoscopic survey".BRITISH JOURNAL OF CANCER 103.7(2010):1085-1088.
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