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学科主题: 临床医学
题名:
Prevalence and risk factors for esophageal squamous cell cancer and precursor lesions in Anyang, China: a population-based endoscopic survey
作者: He, Z.; Zhao, Y.; Guo, C.; Liu, Y.; Sun, M.; Liu, F.; Wang, X.; Guo, F.; Chen, K.; Gao, L.; Ning, T.; Pan, Y.; Li, Y.; Zhang, S.; Lu, C.; Wang, Z.; Cai, H.; Ke, Y.
关键词: prevalence ; risk factor ; esophageal cancer ; precursor lesion ; China
刊名: BRITISH JOURNAL OF CANCER
发表日期: 2010-09-28
DOI: 10.1038/sj.bjc.6605843
卷: 103, 期:7, 页:1085-1088
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Oncology
研究领域[WOS]: Oncology
关键词[WOS]: NUTRITION INTERVENTION TRIAL ; REPUBLIC-OF-CHINA ; GASTRIC CANCERS ; INCIDENT ESOPHAGEAL ; TOOTH LOSS ; FOLLOW-UP ; LINXIAN ; CARCINOMA ; COHORT
英文摘要:

BACKGROUND: The etiology of esophageal squamous cell cancer (ESCC) in high prevalence regions of China remains unclear.

METHODS: Endoscopic biopsies were conducted among 7381 inhabitants aged from 25 to 65 of Anyang, China.

RESULTS: In this study, 2.57, 0.20 and 0.16% of the participants had mild, moderate and severe squamous dysplasia, respectively; 0.19 and 0.08% showed squamous carcinoma in situ and invasive ESCC. Using deep well (depth >100 meters) as water source (odds ratio = 0.72, 95% confidence interval: 0.54-0.96) was negatively associated with ESCC and its precursors, whereas tobacco and alcohol use were not significantly associated with ESCC.

CONCLUSIONS: Water source and other factors in this region need further evaluation by longitudinal studies. British Journal of Cancer (2010) 103, 1085-1088. doi:10.1038/sj.bjc.6605843 www.bjcancer.com Published online 10 August 2010 (C) 2010 Cancer Research UK

语种: 英语
所属项目编号: 30430710 ; 30930102 ; 2006AA2Z467 ; 2006AA02A403 ; 200902002-8 ; 7100001 ; Z09050703080902
项目资助者: Natural Science Foundation of China ; National Ministry of Science and Technology ; Public Welfare Industry of Health ; Natural Science Foundation of Beijing ; Beijing Project on Science and Technology Commission
WOS记录号: WOS:000282222000021
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/56179
Appears in Collections:北京大学临床肿瘤学院_期刊论文

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作者单位: Peking Univ, Sch Oncol, Beijing Canc Hosp & Inst,Lab Genet, Key Lab Carcinogenesis & Translat Res Minist Educ, Beijing 100142, Peoples R China

Recommended Citation:
He, Z.,Zhao, Y.,Guo, C.,et al. Prevalence and risk factors for esophageal squamous cell cancer and precursor lesions in Anyang, China: a population-based endoscopic survey[J]. BRITISH JOURNAL OF CANCER,2010,103(7):1085-1088.
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