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学科主题: 药物依赖
题名:
Review of HIV and HCV infection among drug users in China
作者: Bao, Yan-ping; Liu, Zhi-min; Lu, Lin
关键词: China ; drug users ; HCV ; HIV ; molecular epidemiology
刊名: CURRENT OPINION IN PSYCHIATRY
发表日期: 2010-05-01
DOI: 10.1097/YCO.0b013e328338658b
卷: 23, 期:3, 页:187-194
收录类别: SCI ; SSCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Psychiatry
研究领域[WOS]: Psychiatry
关键词[WOS]: HEPATITIS-C VIRUS ; HUMAN-IMMUNODEFICIENCY-VIRUS ; SOUTHERN CHINA ; CIRCULATING RECOMBINANT ; GENOTYPE DISTRIBUTION ; MOLECULAR EPIDEMIOLOGY ; GENETIC DIVERSITY ; RISK BEHAVIORS ; COMMERCIAL SEX ; TYPE-1 GENOME
英文摘要:

Purpose of review

Drug abuse has resulted in a huge public health and economic burden in China, especially the rapid spread of HIV/AIDS and hepatitis C virus (HCV) infection. Multiple HIV and HCV subtypes were detected among drug users in China, this study reviews the molecular distribution of HIV and HCV among injection drug users (IDUs) and explores new epidemiologic trends of HIV and HCV among drug users in China.

Recent findings

The 2009 National Narcotic Control Commission report showed that the percentage of users of ′new-type drugs′, including amphetamine-type stimulants (ATS: methamphetamine and MDMA/ecstasy) and ketamine, was about 27% of total drug users. The pooled data from published papers showed that CRF07BC was the predominant HIV-1 subtype, which accounted for 38.8%, and it was followed by AE, which accounted for 22.7% among HIV-positive IDUs. Following these, the CRF08BC, B′ and C subtypes accounted for about 10.8%, 9.9% and 9.2%, respectively. Subtype 6a was the predominant HCV subtype, accounting for 36.7%, and subtypes 3b, 1a, 3a and 1b were the next most predominant subtypes.

Summary

With the increase of ′new-type drugs′ use and AE HIV-1 subtype infection among IDUs, the situation regarding HIV/AIDS and HCV infection has become complicated. More comprehensive prevention and intervention strategies should be instigated for the extensive high-risk populations in China.

语种: 英语
所属项目编号: 2007BAI07B04 ; 2008ZX10001-003 ; BMU20090497-123 ; 2009CB522007
项目资助者: Chinese Ministry of Science and Technology ; Research Start-up Foundation of New Teachers of Peking University Medical Center ; National Basic Research Program of China
WOS记录号: WOS:000276448500001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/56191
Appears in Collections:中国药物依赖性研究所_期刊论文

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作者单位: Peking Univ, Natl Inst Drug Dependence, Beijing 100083, Peoples R China

Recommended Citation:
Bao, Yan-ping,Liu, Zhi-min,Lu, Lin. Review of HIV and HCV infection among drug users in China[J]. CURRENT OPINION IN PSYCHIATRY,2010,23(3):187-194.
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