|Review of HIV and HCV infection among drug users in China|
|Bao, Yan-ping; Liu, Zhi-min; Lu, Lin|
|关键词||China Drug Users Hcv Hiv Molecular Epidemiology|
|刊名||CURRENT OPINION IN PSYCHIATRY|
|收录类别||SCI ; SSCI|
|WOS标题词||Science & Technology|
|关键词[WOS]||HEPATITIS-C VIRUS ; HUMAN-IMMUNODEFICIENCY-VIRUS ; SOUTHERN CHINA ; CIRCULATING RECOMBINANT ; GENOTYPE DISTRIBUTION ; MOLECULAR EPIDEMIOLOGY ; GENETIC DIVERSITY ; RISK BEHAVIORS ; COMMERCIAL SEX ; TYPE-1 GENOME|
Purpose of review
Drug abuse has resulted in a huge public health and economic burden in China, especially the rapid spread of HIV/AIDS and hepatitis C virus (HCV) infection. Multiple HIV and HCV subtypes were detected among drug users in China, this study reviews the molecular distribution of HIV and HCV among injection drug users (IDUs) and explores new epidemiologic trends of HIV and HCV among drug users in China.
The 2009 National Narcotic Control Commission report showed that the percentage of users of ′new-type drugs′, including amphetamine-type stimulants (ATS: methamphetamine and MDMA/ecstasy) and ketamine, was about 27% of total drug users. The pooled data from published papers showed that CRF07BC was the predominant HIV-1 subtype, which accounted for 38.8%, and it was followed by AE, which accounted for 22.7% among HIV-positive IDUs. Following these, the CRF08BC, B′ and C subtypes accounted for about 10.8%, 9.9% and 9.2%, respectively. Subtype 6a was the predominant HCV subtype, accounting for 36.7%, and subtypes 3b, 1a, 3a and 1b were the next most predominant subtypes.
With the increase of ′new-type drugs′ use and AE HIV-1 subtype infection among IDUs, the situation regarding HIV/AIDS and HCV infection has become complicated. More comprehensive prevention and intervention strategies should be instigated for the extensive high-risk populations in China.
|项目编号||2007BAI07B04 ; 2008ZX10001-003 ; BMU20090497-123 ; 2009CB522007|
|资助机构||Chinese Ministry of Science and Technology ; Research Start-up Foundation of New Teachers of Peking University Medical Center ; National Basic Research Program of China|
|作者单位||Peking Univ, Natl Inst Drug Dependence, Beijing 100083, Peoples R China|
|Bao, Yan-ping,Liu, Zhi-min,Lu, Lin. Review of HIV and HCV infection among drug users in China[J]. CURRENT OPINION IN PSYCHIATRY,2010,23(3):187-194.|
|APA||Bao, Yan-ping,Liu, Zhi-min,&Lu, Lin.(2010).Review of HIV and HCV infection among drug users in China.CURRENT OPINION IN PSYCHIATRY,23(3),187-194.|
|MLA||Bao, Yan-ping,et al."Review of HIV and HCV infection among drug users in China".CURRENT OPINION IN PSYCHIATRY 23.3(2010):187-194.|