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Review of HIV and HCV infection among drug users in China
Bao, Yan-ping; Liu, Zhi-min; Lu, Lin
关键词China Drug Users Hcv Hiv Molecular Epidemiology
刊名CURRENT OPINION IN PSYCHIATRY
2010-05-01
DOI10.1097/YCO.0b013e328338658b
23期:3页:187-194
收录类别SCI ; SSCI
文章类型Review
WOS标题词Science & Technology
类目[WOS]Psychiatry
研究领域[WOS]Psychiatry
关键词[WOS]HEPATITIS-C VIRUS ; HUMAN-IMMUNODEFICIENCY-VIRUS ; SOUTHERN CHINA ; CIRCULATING RECOMBINANT ; GENOTYPE DISTRIBUTION ; MOLECULAR EPIDEMIOLOGY ; GENETIC DIVERSITY ; RISK BEHAVIORS ; COMMERCIAL SEX ; TYPE-1 GENOME
英文摘要

Purpose of review

Drug abuse has resulted in a huge public health and economic burden in China, especially the rapid spread of HIV/AIDS and hepatitis C virus (HCV) infection. Multiple HIV and HCV subtypes were detected among drug users in China, this study reviews the molecular distribution of HIV and HCV among injection drug users (IDUs) and explores new epidemiologic trends of HIV and HCV among drug users in China.

Recent findings

The 2009 National Narcotic Control Commission report showed that the percentage of users of ′new-type drugs′, including amphetamine-type stimulants (ATS: methamphetamine and MDMA/ecstasy) and ketamine, was about 27% of total drug users. The pooled data from published papers showed that CRF07BC was the predominant HIV-1 subtype, which accounted for 38.8%, and it was followed by AE, which accounted for 22.7% among HIV-positive IDUs. Following these, the CRF08BC, B′ and C subtypes accounted for about 10.8%, 9.9% and 9.2%, respectively. Subtype 6a was the predominant HCV subtype, accounting for 36.7%, and subtypes 3b, 1a, 3a and 1b were the next most predominant subtypes.

Summary

With the increase of ′new-type drugs′ use and AE HIV-1 subtype infection among IDUs, the situation regarding HIV/AIDS and HCV infection has become complicated. More comprehensive prevention and intervention strategies should be instigated for the extensive high-risk populations in China.

语种英语
WOS记录号WOS:000276448500001
项目编号2007BAI07B04 ; 2008ZX10001-003 ; BMU20090497-123 ; 2009CB522007
资助机构Chinese Ministry of Science and Technology ; Research Start-up Foundation of New Teachers of Peking University Medical Center ; National Basic Research Program of China
引用统计
被引频次:29[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/56191
专题中国药物依赖性研究所
作者单位Peking Univ, Natl Inst Drug Dependence, Beijing 100083, Peoples R China
推荐引用方式
GB/T 7714
Bao, Yan-ping,Liu, Zhi-min,Lu, Lin. Review of HIV and HCV infection among drug users in China[J]. CURRENT OPINION IN PSYCHIATRY,2010,23(3):187-194.
APA Bao, Yan-ping,Liu, Zhi-min,&Lu, Lin.(2010).Review of HIV and HCV infection among drug users in China.CURRENT OPINION IN PSYCHIATRY,23(3),187-194.
MLA Bao, Yan-ping,et al."Review of HIV and HCV infection among drug users in China".CURRENT OPINION IN PSYCHIATRY 23.3(2010):187-194.
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