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学科主题临床医学
Purinergic signaling: a novel mechanism in immune surveillance
Mei, Lin1; Du, Wei1; Gao, Wei1; Mei, Qi-bing2
关键词Nucleotides Purinergic Receptor Immune Surveillance Inflammation Chemotaxis
刊名ACTA PHARMACOLOGICA SINICA
2010-09-01
DOI10.1038/aps.2010.128
31期:9页:1149-1153
收录类别SCI
文章类型Review
WOS标题词Science & Technology
类目[WOS]Chemistry, Multidisciplinary ; Pharmacology & Pharmacy
资助者National Natural Science Foundation of China ; National Natural Science Foundation of China
研究领域[WOS]Chemistry ; Pharmacology & Pharmacy
关键词[WOS]P2X(7) RECEPTORS ; EXTRACELLULAR NUCLEOTIDES ; ATP RELEASE ; NEUTROPHIL CHEMOTAXIS ; IN-VIVO ; CELLS ; ACTIVATION ; CANCER ; INJURY ; INFLAMMATION
英文摘要

Purinergic receptors and the associated signaling cascades are known to play critical roles in cardiovascular, nervous, respiratory, gastrointestinal and urinogenital systems. Recent studies have also shed light on the importance of nucleotides and purinergic receptors in the regulation of the immune response. With a better understanding of the distribution and the receptor subtypes, the purinoceptors have the potential to become important therapeutic targets in inflammation, chemotaxis and immune-related diseases.

语种英语
所属项目编号30570757
资助者National Natural Science Foundation of China ; National Natural Science Foundation of China
WOS记录号WOS:000281562900021
引用统计
被引频次:8[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/56251
专题北京大学第三临床医学院_心血管内科
作者单位1.Peking Univ, Hlth Sci Ctr, Dept Cardiol, Hosp 3, Beijing 100191, Peoples R China
2.Fourth Mil Med Univ, Sch Pharm, Dept Pharmacol, Xian 710032, Peoples R China
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GB/T 7714
Mei, Lin,Du, Wei,Gao, Wei,et al. Purinergic signaling: a novel mechanism in immune surveillance[J]. ACTA PHARMACOLOGICA SINICA,2010,31(9):1149-1153.
APA Mei, Lin,Du, Wei,Gao, Wei,&Mei, Qi-bing.(2010).Purinergic signaling: a novel mechanism in immune surveillance.ACTA PHARMACOLOGICA SINICA,31(9),1149-1153.
MLA Mei, Lin,et al."Purinergic signaling: a novel mechanism in immune surveillance".ACTA PHARMACOLOGICA SINICA 31.9(2010):1149-1153.
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