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Noninducibility in Postinfarction Ventricular Tachycardia as an End Point for Ventricular Tachycardia Ablation and Its Effects on Outcomes A Meta-Analysis
Ghanbari, Hamid1; Baser, Kazim1; Yokokawa, Miki1; Stevenson, William2; Della Bella, Paolo3,4; Vergara, Pasquale3,4; Deneke, Thomas5; Kuck, Karl-Heinz6; Kottkamp, Hans7; Fei, She8; Morady, Fred1; Bogun, Frank1
关键词Meta-analysis Tachycardia Ventricular
刊名CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY
2014-08-01
DOI10.1161/CIRCEP.113.001404
7期:4页:677-+
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Cardiac & Cardiovascular Systems
研究领域[WOS]Cardiovascular System & Cardiology
关键词[WOS]CATHETER ABLATION ; HEART-DISEASE ; SINUS RHYTHM ; ISCHEMIC CARDIOMYOPATHY ; RADIOFREQUENCY ABLATION ; SUBSTRATE-MODIFICATION ; MYOCARDIAL-INFARCTION ; SHORT-TERM ; STIMULATION ; SCAR
英文摘要

Background-Although ventricular tachycardia (VT) ablation is a widely used therapy for patients with VT, the ideal end points for this procedure are not well defined. We performed a meta-analysis of the published literature to assess the predictive value of noninducibility of postinfarction VT for long-term outcomes after VT ablation.

Methods and Results-We performed a systematic review of MEDLINE (1950-2013), EMBASE (1988-2013), the Cochrane Controlled Trials Register (Fourth Quarter, 2012), and reports presented at scientific meetings (1994-2013). Randomized controlled trials, case-control, and cohort studies of VT ablation were included. Outcomes reported in eligible studies were freedom from VT/ventricular fibrillation and all-cause mortality. Of the 3895 studies evaluated, we identified 8 cohort studies enrolling 928 patients for the meta-analysis. Noninducibility after VT ablation was associated with a significant increase in arrhythmia-free survival compared with partial success (odds ratio, 0.49; 95% confidence interval, 0.29-0.84; P=0.009) or failed ablation procedure (odds ratio, 0.10; 95% confidence interval, 0.06-0.18; P<0.001). There was also a significant reduction in all-cause mortality if patients were noninducible after VT ablation compared with patients with partial success (odds ratio, 0.59; 95% confidence interval, 0.36-0.98; P=0.04) or failed ablation (odds ratio, 0.32; 95% confidence interval, 0.10-0.99; P=0.049).

Conclusions-Noninducibility of VT after VT ablation is associated with improved arrhythmia-free survival and all-cause mortality.

语种英语
WOS记录号WOS:000341201300020
资助机构Leducq foundation ; Birkhill foundation
引用统计
被引频次:33[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/56276
专题北京大学第三临床医学院_心血管内科
作者单位1.Asklepios Klin St Georg, Hanseat Herzzentrum, Hamburg, Germany
2.Klin Hirslanden, Dept Electrophysiol, Zurich, Switzerland
3.Univ Michigan, Div Cardiol, Dept Internal Med, Ann Arbor, MI 48109 USA
4.Brigham & Women Hosp, Dept Internal Med, Div Cardiovasc, Boston, MA USA
5.Hosp San Raffaele, Arrhythmia Unit, I-20132 Milan, Italy
6.Hosp San Raffaele, Electrophysiol Labs, I-20132 Milan, Italy
7.Herz & Gefass Klin GmbH, Klin Kardiol 2, Bad Neustadt an der Saale, Germany
8.Peking Univ, Hosp 3, Div Cardiol, Dept Internal Med, Beijing 100871, Peoples R China
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GB/T 7714
Ghanbari, Hamid,Baser, Kazim,Yokokawa, Miki,et al. Noninducibility in Postinfarction Ventricular Tachycardia as an End Point for Ventricular Tachycardia Ablation and Its Effects on Outcomes A Meta-Analysis[J]. CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY,2014,7(4):677-+.
APA Ghanbari, Hamid.,Baser, Kazim.,Yokokawa, Miki.,Stevenson, William.,Della Bella, Paolo.,...&Bogun, Frank.(2014).Noninducibility in Postinfarction Ventricular Tachycardia as an End Point for Ventricular Tachycardia Ablation and Its Effects on Outcomes A Meta-Analysis.CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY,7(4),677-+.
MLA Ghanbari, Hamid,et al."Noninducibility in Postinfarction Ventricular Tachycardia as an End Point for Ventricular Tachycardia Ablation and Its Effects on Outcomes A Meta-Analysis".CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY 7.4(2014):677-+.
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