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IR@PKUHSC  > 北京大学临床肿瘤学院  > 超声科  > 期刊论文
学科主题: 临床医学
题名:
Contrast-enhanced ultrasound versus conventional ultrasound in the diagnosis of polypoid lesion of gallbladder: A multi-center study of dynamic microvascularization
作者: Zheng, Shu-Guang1,2; Xu, Hui-Xiong1,2; Liu, Lin-Na1; Lu, Ming-De2; Xie, Xiao-Yan2; Wang, Wen-Ping3; Hu, Bing4; Yan, Kun5; Ding, Hong3; Tang, Shao-Shan6; Qian, Lin-Xue7; Luo, Bao-Ming8
关键词: Contrast-enhanced ultrasound ; gallbladder ; polypoid lesion ; differential diagnosis
刊名: CLINICAL HEMORHEOLOGY AND MICROCIRCULATION
发表日期: 2013
DOI: 10.3233/CH-121651
卷: 55, 期:3, 页:359-374
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Hematology ; Peripheral Vascular Disease
研究领域[WOS]: Hematology ; Cardiovascular System & Cardiology
关键词[WOS]: ENDOSCOPIC ULTRASONOGRAPHY ; DIFFERENTIAL-DIAGNOSIS ; COMPUTED-TOMOGRAPHY ; US FINDINGS ; FOLLOW-UP ; DISEASES ; SONOGRAPHY ; CHOLECYSTITIS ; PERFORMANCE ; PREVALENCE
英文摘要:

OBJECTIVE: To assess the value of contrast-enhanced ultrasound (CEUS) in the diagnosis of polypoid lesions of gallbladder (PLGs).

METHODS: CEUS was performed to 116 patients (mean age, 49.6 years; range, 21-80 years) with PLGs from 8 university hospitals. 9 cases of biliary sludge were proven by surgery and the remaining 107 cases were confirmed by histopathological examination. The confidence level, diagnostic performance, inter-observer agreement of two independent readers with different experience was assessed. The readers were blind to the imaging and clinical results of the patients.

RESULTS: There were significant differences between benign and malignant PLGs in patient age, gender, lesion size, echogenicity, stalk, time-to-peak, vascularity on CEUS, enhancement pattern, and wall destruction. The confidence levels increased significantly and the interobserver agreement increased from 0.425 to 0.601 after CEUS. The sensitivity increased from 22.2 to 77.8% after CEUS in the staff radiologist, and from 22.2 to 66.7% in the resident radiologist. The correctly characterized lesions were 64.7% before versus 87.1% after CEUS (P = 0.125) for the staff radiologist, and 57.8% versus 70.7% for the resident radiologist (P = 0.007). No significance was found in the subgroup of lesions <= 1.0 cm before and after CEUS for the two radiologists.

CONCLUSIONS: CEUS using convex multifrequency probes could detect the dynamic microvascularization of PLGs greater than 1.0 cm and facilitate the differentiation between benign and malignant tumors.

语种: 英语
所属项目编号: 2008-2-10 ; 20114003
项目资助者: Public Welfare Research Special Project from Chinese Ministry of Health ; Key Project of Shanghai Health Bureau
WOS记录号: WOS:000328959000008
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/56460
Appears in Collections:北京大学临床肿瘤学院_超声科_期刊论文

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作者单位: 1.Tongji Univ, Peoples Hosp 10, Dept Med Ultrasound, Shanghai Peoples Hosp 10, Shanghai 200092, Peoples R China
2.Sun Yat Sen Univ, Affiliated Hosp 1, Dept Med Ultrason, Guangzhou 510275, Guangdong, Peoples R China
3.Fudan Univ, Zhongshan Hosp, Dept Ultrasound, Shanghai 200433, Peoples R China
4.Shanghai Jiao Tong Univ, Affiliated Peoples Hosp 6, Dept Ultrasound Med, Shanghai 200030, Peoples R China
5.Peking Univ, Sch Oncol, Beijing Canc Inst, Dept Ultrasound, Beijing 100871, Peoples R China
6.China Med Univ, Shengjing Hosp, Dept Ultrasound, Shenyang, Peoples R China
7.Capital Med Univ, Beijing Friendship Hosp, Dept Ultrasound, Beijing, Peoples R China
8.Sun Yat Sen Univ, Affiliated Hosp 2, Dept Ultrasound, Guangzhou 510275, Guangdong, Peoples R China

Recommended Citation:
Zheng, Shu-Guang,Xu, Hui-Xiong,Liu, Lin-Na,et al. Contrast-enhanced ultrasound versus conventional ultrasound in the diagnosis of polypoid lesion of gallbladder: A multi-center study of dynamic microvascularization[J]. CLINICAL HEMORHEOLOGY AND MICROCIRCULATION,2013,55(3):359-374.
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