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学科主题临床医学
An investigation of (125)vertical bar seed permanent implantation for recurrent carcinoma in the head and neck after surgery and external beam radiotherapy
Zhu, Lihong1; Jiang, Yuliang1; Wang, Junjie1; Ran, Weiqiang2; Yuan, Huishu3; Liu, Chen3; Qu, Ang1; Yang, Ruijie1
关键词(125)Vertical Bar Seed Head And Neck Carcinoma Surgery External Beam Radiotherapy
刊名WORLD JOURNAL OF SURGICAL ONCOLOGY
2013-03-08
DOI10.1186/1477-7819-11-60
11
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Oncology ; Surgery
研究领域[WOS]Oncology ; Surgery
关键词[WOS]SQUAMOUS-CELL CANCER ; RADIATION-THERAPY ; CAROTID-ARTERY ; I125 IMPLANTS ; REIRRADIATION ; TONGUE ; 5-FLUOROURACIL ; BRACHYTHERAPY ; NASOPHARYNX ; IRRADIATION
英文摘要

Background: A preliminary assessment was conducted of the feasibility, efficacy, and morbidity of (125)vertical bar seed implantation for recurrent head and neck carcinoma after surgery and external beam radiotherapy.

Methods: Nineteen patients with recurrent head and neck carcinomas underwent (125)vertical bar seed implantation under ultrasound or computed tomography guidance. The actuarial D90 of (125)vertical bar seed implantation ranged from 90 to 160 Gy (median, 131 Gy). The follow-up period ranged from 3 to 44 months (median, 11 months).

Results: The median local control was 24 months (95% confidence interval, 10.2 to 37.8). The one- year, two-year and three-year local controls were 73.3%, 27.5% and 27.5%, respectively, whereas the one-year, two-year and three-year survival rates were 53.0%, 18.2% and 18.2%, respectively, and the median survival was 13 months (95% confidence interval, 6.6 to 19.4). A total of 26.3% of patients (5/19) died of local recurrence and 21.1% of patients (4/19) died of metastases. One suffered from a grade 1 skin reaction.

Conclusions: (125)vertical bar seed implantation is feasible and safe as a salvage treatment for patients with recurrent head and neck cancers. The high local control results and low morbidity merits further investigation.

语种英语
WOS记录号WOS:000316764700001
资助机构Capital Medical Development Grant of Beijing
引用统计
被引频次:18[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/56494
专题北京大学第三临床医学院_肿瘤放疗科
北京大学第三临床医学院_肿瘤治疗中心
北京大学精神卫生研究所_护理部
作者单位1.Peking Univ, Dept Radiat Oncol, Hosp 3, Beijing 100191, Peoples R China
2.Peking Univ, Dept Ultrasound, Hosp 3, Beijing 100191, Peoples R China
3.Peking Univ, Dept Radiol, Hosp 3, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Zhu, Lihong,Jiang, Yuliang,Wang, Junjie,et al. An investigation of (125)vertical bar seed permanent implantation for recurrent carcinoma in the head and neck after surgery and external beam radiotherapy[J]. WORLD JOURNAL OF SURGICAL ONCOLOGY,2013,11.
APA Zhu, Lihong.,Jiang, Yuliang.,Wang, Junjie.,Ran, Weiqiang.,Yuan, Huishu.,...&Yang, Ruijie.(2013).An investigation of (125)vertical bar seed permanent implantation for recurrent carcinoma in the head and neck after surgery and external beam radiotherapy.WORLD JOURNAL OF SURGICAL ONCOLOGY,11.
MLA Zhu, Lihong,et al."An investigation of (125)vertical bar seed permanent implantation for recurrent carcinoma in the head and neck after surgery and external beam radiotherapy".WORLD JOURNAL OF SURGICAL ONCOLOGY 11(2013).
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