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学科主题: 临床医学
题名:
A circumferential decompression-based surgical strategy for multilevel ossification of thoracic posterior longitudinal ligament
作者: Hu, Panpan; Yu, Miao; Liu, Xiaoguang; Liu, Zhongjun; Jiang, Liang
关键词: Circumferential decompression ; Intraoperative ultrasound ; Multilevel ; Ossification of posterior longitudinal ligament ; Surgical strategy ; Thoracic
刊名: SPINE JOURNAL
发表日期: 2015-12-01
DOI: 10.1016/j.spinee.2015.08.060
卷: 15, 期:12, 页:2484-2492
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Clinical Neurology ; Orthopedics
研究领域[WOS]: Neurosciences & Neurology ; Orthopedics
关键词[WOS]: SPINAL-CORD DECOMPRESSION ; MYELOPATHY ; SURGERY ; FLAVUM ; FUSION
英文摘要:

BACKGROUND CONTEXT: Multilevel ossification of posterior longitudinal ligament (OPLL) at thoracic spine can be simultaneously symptomatic. Different approaches for thoracic decompression have been reported, among which circumferential decompression (CD) seems promising but is invasive, so methods to find approaches indicating levels for CD are also important.

PURPOSE: This study aimed to introduce a CD-based surgical strategy for multilevel thoracic OPLL and describe its clinical outcomes.

STUDY DESIGN: A retrospective clinical study was used.

PATIENT SAMPLE: Acohort of 26 patients were recruited, whose average age was 51.2 +/- 9.1 years old.

OUTCOME MEASURES: A modified Japanese Orthopedic Association (JOA) scale for thoracic spine was used to evaluate neurologic status, and final recovery rates were assessed according to Hirabayashi system.

METHODS: Posterior decompression was initially performed for all compressive levels, whereas CD levels were decided through combined modalities, of which intraoperative ultrasound was an important determinant. All patients were regularly followed for more than 2 years.

RESULTS: The average operative duration and blood loss were 279.3 +/- 54.8 minutes and 2257.7 +/- 1443.9 mL, respectively. There were 17 patients (65.4%) who achieved instant improvement and 9 (34.6%) neurologically deteriorated. Cerebrospinal fluid leakage occurred in 10 patients (38.5%), but its occurrence did not affect the final neurologic recovery. Other complications included urinary infection, incision infection and disunion, lung infection, and subcutaneous fluid collection. Late events included death from cerebrovascular accident, pseudomeningocele, unremitted intercostal pain and continuing deterioration. The final JOA score and recovery rate were correlated with OPLL levels and preoperative JOA scores (p < .05). Eventually, the average JOA score was significantly elevated from 4.5 +/- 1.8 to 8.3 +/- 2.3 (p < .05), with the recovery rate of 11 patients rated as excellent, 7 as good, 6 as fair, and 2 as unchanged or deteriorated. The average recovery rate was 60.4%.

CONCLUSIONS: This CD-based surgical strategy was effective for multilevel thoracic OPLL and had fair late outcomes, but its postoperative courses were quite eventful. Intraoperative ultrasound was a reliable modality to determine CD levels. (C) 2015 Elsevier Inc. All rights reserved.

语种: 英语
所属项目编号: Z141107002514011 ; 2013-136
项目资助者: Capital Foundation of Characteristic Clinical Practice and Research ; Foundation of Science and Research Projects for Capital Health Development
WOS记录号: WOS:000366655100042
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/56528
Appears in Collections:北京大学第三临床医学院_骨科_期刊论文

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作者单位: Peking Univ, Hosp 3, Dept Orthopaed, Beijing 100191, Peoples R China

Recommended Citation:
Hu, Panpan,Yu, Miao,Liu, Xiaoguang,et al. A circumferential decompression-based surgical strategy for multilevel ossification of thoracic posterior longitudinal ligament[J]. SPINE JOURNAL,2015,15(12):2484-2492.
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