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学科主题临床医学
Dialysis adequacy in Chinese anuric peritoneal dialysis patients
Shao, Yeqing1; Ma, Sha1; Tian, Xiangyin1; Wang, Tao2; Xu, Jiayun1
关键词Peritoneal Dialysis Anuria Dialysis Adequacy Low-protein Diet
刊名INTERNATIONAL UROLOGY AND NEPHROLOGY
2013-10-01
DOI10.1007/s11255-013-0379-1
45期:5页:1429-1436
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Urology & Nephrology
研究领域[WOS]Urology & Nephrology
关键词[WOS]CHRONIC-RENAL-FAILURE ; DOQI GUIDELINES ; CAPD PATIENTS ; NUTRITION ; SURVIVAL ; PROTEIN ; KT/V ; MORTALITY ; TARGETS ; DIET
英文摘要

We aimed in this study to explore how lower-protein diet would affect dialysis adequacy in anuric peritoneal dialysis (PD) patients.

Patients′ demographic features were collected, namely age, gender, weight, height, underlying renal disease, and time on PD. Urea kinetic model was used to assess solute clearance. A consecutive 3-day dietary record was collected to evaluate dietary protein intake (DPI), and normalized protein nitrogen appearance (nPNA) was also calculated to reflect protein intake. Blood samples were collected to measure hemoglobin and biochemistry. Patient′s nutritional status was assessed by biochemistry, handgrip strength, and subjective global assessment (SGA). Body fluid distribution was measured by body composition monitor.

Patients were 60.8 +/- A 14.92 years old, and the time on PD was 40.15 +/- A 22.90 months. Daily prescribed dialysis dose was 7,178 +/- A 1,326 mL. Kt/V was 1.6 +/- A 0.32. DPI was 0.8 +/- A 0.25 g/kg/day. nPNA was 0.9 +/- A 0.21 g/kg/day. Serum albumin was 39.42 +/- A 4.83 g/L. Prevalence of malnutrition (assessed by SGA) was 20.2 %. Serum phosphate and serum bicarbonate were 1.68 +/- A 0.47 and 27.16 +/- A 3.49 mmol/L, respectively. Systolic blood pressure and diastolic blood pressure were 123.4 +/- A 20.0 and 74.2 +/- A 12.6 mmHg, respectively. Patients with nPNA less than 0.6 had significantly lower serum albumin concentrations than the average, and patients with nPNA more than 1.2 g/kg/day had significantly higher levels of serum phosphate and serum urea than the average.

Our study suggested that anuric PD patients could achieve adequate dialysis even under lower solute clearance. And lower-protein diet contributed largely to adequate dialysis in these patients.

语种英语
WOS记录号WOS:000325696900022
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/56607
专题北京大学第三临床医学院_肾内科
北京大学公共卫生学院_公共卫生学院
作者单位1.Henan Univ Sci & Technol, Dept Nephrol, Affiliated Hosp 1, Luoyang, Peoples R China
2.Peking Univ, Hosp 3, Div Nephrol, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714
Shao, Yeqing,Ma, Sha,Tian, Xiangyin,et al. Dialysis adequacy in Chinese anuric peritoneal dialysis patients[J]. INTERNATIONAL UROLOGY AND NEPHROLOGY,2013,45(5):1429-1436.
APA Shao, Yeqing,Ma, Sha,Tian, Xiangyin,Wang, Tao,&Xu, Jiayun.(2013).Dialysis adequacy in Chinese anuric peritoneal dialysis patients.INTERNATIONAL UROLOGY AND NEPHROLOGY,45(5),1429-1436.
MLA Shao, Yeqing,et al."Dialysis adequacy in Chinese anuric peritoneal dialysis patients".INTERNATIONAL UROLOGY AND NEPHROLOGY 45.5(2013):1429-1436.
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