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学科主题: 临床医学
题名:
Dialysis adequacy in Chinese anuric peritoneal dialysis patients
作者: Shao, Yeqing1; Ma, Sha1; Tian, Xiangyin1; Wang, Tao2; Xu, Jiayun1
关键词: Peritoneal dialysis ; Anuria ; Dialysis adequacy ; Low-protein diet
刊名: INTERNATIONAL UROLOGY AND NEPHROLOGY
发表日期: 2013-10-01
DOI: 10.1007/s11255-013-0379-1
卷: 45, 期:5, 页:1429-1436
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Urology & Nephrology
研究领域[WOS]: Urology & Nephrology
关键词[WOS]: CHRONIC-RENAL-FAILURE ; DOQI GUIDELINES ; CAPD PATIENTS ; NUTRITION ; SURVIVAL ; PROTEIN ; KT/V ; MORTALITY ; TARGETS ; DIET
英文摘要:

We aimed in this study to explore how lower-protein diet would affect dialysis adequacy in anuric peritoneal dialysis (PD) patients.

Patients′ demographic features were collected, namely age, gender, weight, height, underlying renal disease, and time on PD. Urea kinetic model was used to assess solute clearance. A consecutive 3-day dietary record was collected to evaluate dietary protein intake (DPI), and normalized protein nitrogen appearance (nPNA) was also calculated to reflect protein intake. Blood samples were collected to measure hemoglobin and biochemistry. Patient′s nutritional status was assessed by biochemistry, handgrip strength, and subjective global assessment (SGA). Body fluid distribution was measured by body composition monitor.

Patients were 60.8 +/- A 14.92 years old, and the time on PD was 40.15 +/- A 22.90 months. Daily prescribed dialysis dose was 7,178 +/- A 1,326 mL. Kt/V was 1.6 +/- A 0.32. DPI was 0.8 +/- A 0.25 g/kg/day. nPNA was 0.9 +/- A 0.21 g/kg/day. Serum albumin was 39.42 +/- A 4.83 g/L. Prevalence of malnutrition (assessed by SGA) was 20.2 %. Serum phosphate and serum bicarbonate were 1.68 +/- A 0.47 and 27.16 +/- A 3.49 mmol/L, respectively. Systolic blood pressure and diastolic blood pressure were 123.4 +/- A 20.0 and 74.2 +/- A 12.6 mmHg, respectively. Patients with nPNA less than 0.6 had significantly lower serum albumin concentrations than the average, and patients with nPNA more than 1.2 g/kg/day had significantly higher levels of serum phosphate and serum urea than the average.

Our study suggested that anuric PD patients could achieve adequate dialysis even under lower solute clearance. And lower-protein diet contributed largely to adequate dialysis in these patients.

语种: 英语
WOS记录号: WOS:000325696900022
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/56607
Appears in Collections:北京大学第三临床医学院_肾内科_期刊论文

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作者单位: 1.Henan Univ Sci & Technol, Dept Nephrol, Affiliated Hosp 1, Luoyang, Peoples R China
2.Peking Univ, Hosp 3, Div Nephrol, Beijing 100871, Peoples R China

Recommended Citation:
Shao, Yeqing,Ma, Sha,Tian, Xiangyin,et al. Dialysis adequacy in Chinese anuric peritoneal dialysis patients[J]. INTERNATIONAL UROLOGY AND NEPHROLOGY,2013,45(5):1429-1436.
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