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学科主题临床医学
Clinical Features and Treatment Options for Chinese Patients With Severe Primary Erectile Dysfunction
Zhu, Yi-Chen; Zhao, Jing-Liang; Wu, Yi-guang; Yuan, Yi-Ming; Lian, Wen-Qing; Zhang, Jian; Cui, Wan-Shou; Zhe, Jin; Xin, Zhong-cheng1
刊名UROLOGY
2010-08-01
DOI10.1016/j.urology.2009.12.008
76期:2页:387-390
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Urology & Nephrology
研究领域[WOS]Urology & Nephrology
关键词[WOS]INFLATABLE PENILE PROSTHESIS ; SATISFACTION ; EPIDEMIOLOGY ; PREVALENCE ; IMPOTENCE ; SAFETY ; MEN
英文摘要

OBJECTIVES To investigate clinical features of Chinese patients with severe primary erectile dysfunction (S-PED) and to identify the ideal treatment options for this population.

METHODS Patients with PED were screened for enrollment in our study. Sexual history, marital status, and erectile function were evaluated by inquiry including International Index of Erectile Function-5. Individuals with severe PED (defined as refractory to management with phosphodiesterase type 5 inhibitor [PDE5i]) underwent serum hormone analysis, penile color duplex Doppler ultrasound, neuroelectromyogram, and cavernosography as appropriate. Long-term treatment results were determined.

RESULTS Among 220 PED patients, 72 (32.7%) suffered from severe PED (PDE5i nonresponse). Mean age was 31.5 +/- 4.5 years and mean duration of attempts at sexual activity was 2.4 +/- 3.2 years, Sixty-eight men (94.5%) had organic etiologies for erectile dysfunction, including arteriogenic (n = 13), venogenic (n = 35), endocrinologic (n = 6), neurologic (n = 9), and cavernosal fibrosis (n = 5). Sixteen men (22.2%) had been divorced. Mean erectile function and quality-of-life were significantly improved (P < .001) in the 25 men (34.7%) who were treated by penile prosthesis implantation, at a mean follow-up of 5.6 years. Satisfaction with penile prosthesis for patients and partner was 93.4% and 92.3%, respectively.

CONCLUSIONS Severe PED has a major impact on young couple′s life quality. Venous leak is the most common cause of severe PED. Penile prosthesis implantation is safe and effective for severe PED. UROLOGY 76: 387-390, 2010. (C) 2010 Elsevier Inc.

语种英语
WOS记录号WOS:000280865300044
引用统计
被引频次:5[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/56662
专题北京大学第一临床医学院_泌尿外科
作者单位1.Peking Univ, Peking Univ Hosp 1, Inst Urol, Androl Ctr, Beijing 100034, Peoples R China
2.Second Hosp Qinhuangdao City, Dept Urol, Qinhuangdao, Hebei, Peoples R China
推荐引用方式
GB/T 7714
Zhu, Yi-Chen,Zhao, Jing-Liang,Wu, Yi-guang,et al. Clinical Features and Treatment Options for Chinese Patients With Severe Primary Erectile Dysfunction[J]. UROLOGY,2010,76(2):387-390.
APA Zhu, Yi-Chen.,Zhao, Jing-Liang.,Wu, Yi-guang.,Yuan, Yi-Ming.,Lian, Wen-Qing.,...&Xin, Zhong-cheng.(2010).Clinical Features and Treatment Options for Chinese Patients With Severe Primary Erectile Dysfunction.UROLOGY,76(2),387-390.
MLA Zhu, Yi-Chen,et al."Clinical Features and Treatment Options for Chinese Patients With Severe Primary Erectile Dysfunction".UROLOGY 76.2(2010):387-390.
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