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学科主题: 临床医学
题名:
Identification of Obstructive Sleep Apnea Syndrome by Ambulatory Electrocardiography: Clinical Evaluation of Time-domain and Frequency-domain Analyses of Heart Rate Variability in Chinese Patients
作者: Sun Jianling1; Li Xiaoying2; Guo Jihong3; Han Fang4; Zhang Haicheng3
关键词: Sleep apnea syndrome ; Heart rate variability ; Time-domain analysis ; Frequency-domain analysis ; Ambulatory electrocardiogram monitoring
刊名: CELL BIOCHEMISTRY AND BIOPHYSICS
发表日期: 2011-04-01
DOI: 10.1007/s12013-010-9128-6
卷: 59, 期:3, 页:165-170
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Biochemistry & Molecular Biology ; Biophysics ; Cell Biology
研究领域[WOS]: Biochemistry & Molecular Biology ; Biophysics ; Cell Biology
关键词[WOS]: ADULTS
英文摘要:

The application of ambulatory electrocardiography to identify obstructive sleep apnea syndrome (OSAS) patients was evaluated using time-domain and frequency-domain analyses of heart rate variability (HRV). For this, overnight sleep pattern was investigated in 95 individuals (48 OSAS(+) patients and 47 OSAS(-) controls) by polysomnography and 24-h ambulatory electrocardiography. Apnea scores were calculated using two different HRV analyses. Average age and body mass index, and percentages of men and of patients with history of hypertension and/or diabetes were higher in study group as compared with control group. PNN50(night), SDNNI(day-night) and SDNNI(day-night) in time-domain analysis were more sensitive than other indices. In frequency-domain analysis, mean night-time total power, night-time VLF power, night-time LF power, and the difference between these measures in day and night were significantly higher in study group. LF/HF ratio was also significantly higher in study group in day-time or night-time with a significant difference (P < 0.05) between day and night. At sleep apnea risk score > 4, sensitivity, specificity, and positive predictive value were, respectively, 81.25, 46.81, and 64.21%. At sleep apnea risk scores > 5, 6, or 7, the specificity increased, while the sensitivity and positive predictive value decreased. In conclusion, time-domain and frequency-domain HRV analyses are useful methods for OSAS screening, and the frequency-domain analysis is more sensitive.

语种: 英语
WOS记录号: WOS:000288388600005
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/56713
Appears in Collections:北京大学第二临床医学院_心血管内科_期刊论文

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作者单位: 1.Aviat Ind Cent Hosp, Dept Cardiol, Beijing 100012, Peoples R China
2.Chinese Peoples Liberat Army Gen Hosp, Dept Geriatr Cardiol, Beijing, Peoples R China
3.Peking Univ, Peoples Hosp, Dept Cardiol, Electrophysiol Grp, Beijing 100871, Peoples R China
4.Peking Univ, Peoples Hosp, Dept Respirat, Sleep Ctr, Beijing 100871, Peoples R China

Recommended Citation:
Sun Jianling,Li Xiaoying,Guo Jihong,et al. Identification of Obstructive Sleep Apnea Syndrome by Ambulatory Electrocardiography: Clinical Evaluation of Time-domain and Frequency-domain Analyses of Heart Rate Variability in Chinese Patients[J]. CELL BIOCHEMISTRY AND BIOPHYSICS,2011,59(3):165-170.
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