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学科主题: 临床医学
题名:
The Use of FTIR-ATR Spectrometry for Evaluation of Surgical Resection Margin in Colorectal Cancer: A Pilot Study of 56 Samples
作者: Yao, Hongwei1; Shi, Xueying2; Zhang, Yuanfu3
刊名: JOURNAL OF SPECTROSCOPY
发表日期: 2014
DOI: 10.1155/2014/213890
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Biochemical Research Methods ; Spectroscopy
研究领域[WOS]: Biochemistry & Molecular Biology ; Spectroscopy
关键词[WOS]: TRANSFORM INFRARED-SPECTROSCOPY ; TISSUES ; IR ; DIAGNOSIS
英文摘要:

Colorectal cancer is one of the most common malignancies in human, and it is also one of the most leading causes of cancer-related death. Recently, Fourier transform infrared (FTIR) spectrometry is considered to develop into a new method for cancer diagnosis. In this study, colorectal cancer and mucosa 1 cm, 2 cm, and 5 cm away from tumor were measured by FTIR spectroscopy. FTIR spectra of colorectal cancer and mucosa 1 cm away from tumor were different from those of mucosa 2 cm and 5 cm away from tumor. According to the analysis of FTIR spectrometry, the decrease of lipid and the increase of protein and nucleic acid were observed in the former two sites. FTIR spectrometry, therefore, may be developed into a rapid promising method for judging surgical resection margin of colorectal cancer.

语种: 英语
所属项目编号: 2010D009001000-005
项目资助者: Foundation of Beijing Excellent Talent Training Project
WOS记录号: WOS:000330484200001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/56725
Appears in Collections:北京大学第三临床医学院_普通外科_期刊论文

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作者单位: 1.Peking Univ, Hosp 3, Dept Gen Surg, Beijing 100191, Peoples R China
2.Peking Univ, Hosp 3, Dept Pathol, Sch Basic Med Sci, Beijing 100191, Peoples R China
3.Peking Univ, Coll Chem & Mol Engn, State Key Lab Rare Earth Mat Chem & Applicat, Beijing 100871, Peoples R China

Recommended Citation:
Yao, Hongwei,Shi, Xueying,Zhang, Yuanfu. The Use of FTIR-ATR Spectrometry for Evaluation of Surgical Resection Margin in Colorectal Cancer: A Pilot Study of 56 Samples[J]. JOURNAL OF SPECTROSCOPY,2014.
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