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Comparison of integrated traditional Chinese and western medicine therapy on vascular cognitive impairment with no dementia
Wang, L. P.1; Zhang, X. Y.1; Liu, N.1; Ma, Z. Z.2; Fang, D. S.1
关键词Chinese Traditional Medicine Western Medicine Vascular Cognitive Impairment With No Dementia Ginkgo Tablet Cognitive Function Cerebral Blood Flow
刊名GENETICS AND MOLECULAR RESEARCH
2015
DOI10.4238/2015.May.11.22
14期:2页:4896-4902
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biochemistry & Molecular Biology ; Genetics & Heredity
研究领域[WOS]Biochemistry & Molecular Biology ; Genetics & Heredity
关键词[WOS]ALZHEIMERS-DISEASE ; ASSESSMENT MOCA ; GINKGO-BILOBA
英文摘要

The aim of this study was to investigate the clinical effect of western medicine therapy assisted by Ginkgo biloba tablets (GBT) in patients with vascular cognitive impairment with no dementia (VCIND). Eighty patients with VCIND were randomly divided into two groups: the conventional treatment group (control group) and the combined treatment group. The conventional treatment group was provided with anti-platelet aggregation conventional treatment. In this group, 75 mg aspirin was given three times a day for 3 months, whereas the combined treatment group was given 19.2 mg GBT three times a day for 3 months along with conventional anti-platelet aggregation treatment. Montreal cognitive assessment (MoCA) and transcranial Doppler ultrasonography were used to observe changes in cognitive ability and cerebral blood flow in patients with VCIND before and after treatment in the two groups. After 3 months of treatment, the MoCA scores of execution, attention, abstraction, delayed memory, and orientation were significantly increased in the combined treatment group compared with those before treatment and those in the control group after treatment. In addition, the blood flow velocity of the anterior cerebral artery was significantly increased in the combined treatment group. GBT can improve the therapeutic efficacy, cognitive ability, and cerebral blood flow supply of patients with VCIND.

语种英语
WOS记录号WOS:000357183700209
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/56767
专题北京大学第三临床医学院_神经内科
作者单位1.Peking Univ, Hosp 3, Dept Neurol, Beijing 100871, Peoples R China
2.Peking Univ, Hlth Sci Ctr, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714
Wang, L. P.,Zhang, X. Y.,Liu, N.,et al. Comparison of integrated traditional Chinese and western medicine therapy on vascular cognitive impairment with no dementia[J]. GENETICS AND MOLECULAR RESEARCH,2015,14(2):4896-4902.
APA Wang, L. P.,Zhang, X. Y.,Liu, N.,Ma, Z. Z.,&Fang, D. S..(2015).Comparison of integrated traditional Chinese and western medicine therapy on vascular cognitive impairment with no dementia.GENETICS AND MOLECULAR RESEARCH,14(2),4896-4902.
MLA Wang, L. P.,et al."Comparison of integrated traditional Chinese and western medicine therapy on vascular cognitive impairment with no dementia".GENETICS AND MOLECULAR RESEARCH 14.2(2015):4896-4902.
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