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学科主题: 临床医学
题名:
Comparison of integrated traditional Chinese and western medicine therapy on vascular cognitive impairment with no dementia
作者: Wang, L. P.1; Zhang, X. Y.1; Liu, N.1; Ma, Z. Z.2; Fang, D. S.1
关键词: Chinese traditional medicine ; Western medicine ; Vascular cognitive impairment with no dementia ; Ginkgo tablet ; Cognitive function ; Cerebral blood flow
刊名: GENETICS AND MOLECULAR RESEARCH
发表日期: 2015
DOI: 10.4238/2015.May.11.22
卷: 14, 期:2, 页:4896-4902
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Biochemistry & Molecular Biology ; Genetics & Heredity
研究领域[WOS]: Biochemistry & Molecular Biology ; Genetics & Heredity
关键词[WOS]: ALZHEIMERS-DISEASE ; ASSESSMENT MOCA ; GINKGO-BILOBA
英文摘要:

The aim of this study was to investigate the clinical effect of western medicine therapy assisted by Ginkgo biloba tablets (GBT) in patients with vascular cognitive impairment with no dementia (VCIND). Eighty patients with VCIND were randomly divided into two groups: the conventional treatment group (control group) and the combined treatment group. The conventional treatment group was provided with anti-platelet aggregation conventional treatment. In this group, 75 mg aspirin was given three times a day for 3 months, whereas the combined treatment group was given 19.2 mg GBT three times a day for 3 months along with conventional anti-platelet aggregation treatment. Montreal cognitive assessment (MoCA) and transcranial Doppler ultrasonography were used to observe changes in cognitive ability and cerebral blood flow in patients with VCIND before and after treatment in the two groups. After 3 months of treatment, the MoCA scores of execution, attention, abstraction, delayed memory, and orientation were significantly increased in the combined treatment group compared with those before treatment and those in the control group after treatment. In addition, the blood flow velocity of the anterior cerebral artery was significantly increased in the combined treatment group. GBT can improve the therapeutic efficacy, cognitive ability, and cerebral blood flow supply of patients with VCIND.

语种: 英语
WOS记录号: WOS:000357183700209
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/56767
Appears in Collections:北京大学第三临床医学院_神经内科_期刊论文

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作者单位: 1.Peking Univ, Hosp 3, Dept Neurol, Beijing 100871, Peoples R China
2.Peking Univ, Hlth Sci Ctr, Beijing 100871, Peoples R China

Recommended Citation:
Wang, L. P.,Zhang, X. Y.,Liu, N.,et al. Comparison of integrated traditional Chinese and western medicine therapy on vascular cognitive impairment with no dementia[J]. GENETICS AND MOLECULAR RESEARCH,2015,14(2):4896-4902.
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