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学科主题: 临床医学
题名:
Prevalence of chronic obstructive pulmonary disease in China - A large, population-based survey
作者: Zhong, Nanshan; Wang, Chen; Yao, Wanzhen; Chen, Ping; Kang, Jian; Huang, Shaoguang; Chen, Baoyuan; Wang, Changzheng; Ni, Diantao; Zhou, Yumin; Liu, Shengming; Wang, Xiaoping; Wang, Dali; Lu, Jiachun; Zheng, Jingping; Ran, Pixin
关键词: chronic obstructive pulmonary disease ; prevalence ; epidemiology ; cross-sectional studies ; GOLD
刊名: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
发表日期: 2007-10-15
DOI: 10.1164/rccm.200612-17490C
卷: 176, 期:8, 页:753-760
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Critical Care Medicine ; Respiratory System
研究领域[WOS]: General & Internal Medicine ; Respiratory System
关键词[WOS]: LUNG-DISEASE ; COPD PREVALENCE ; NORTHERN SWEDEN ; GLOBAL BURDEN ; SMOKING ; UNDERDIAGNOSIS ; SAMPLE
英文摘要:

Rationale: The prevalence of chronic obstructive pulmonary disease (COPD) in China is largely unknown.

Objectives: To obtain the COPD prevalence in China through a largepopulation, spirometry-based, cross-sectional survey of COPD.

Methods: Urban and rural population-based cluster samples were randomly selected from seven provinces/cities. All residents 40years of age or older in the selected clusters were interviewed with a standardized questionnaire revised from the international BOLD (Burden of Obstructive Lung Diseases) study. Spirometry was performed on all eligible participants. Patients with airflow limitation (FEV1/FVC < 0.70) were further examined by post-bronchodilator spirometry, chest radiograph, and electrocardiogram. Post-bronchodilator FEV1/ FVC of less than 70%was defined as the diagnostic criterion of COPD.

Measurements and Main Results: Among 25,627 sampling subjects, 20,245 participants completed the questionnaire and spirometry (response rate, 79.0%). The overall prevalence of COPD was 8.2% (men, 12.4%; women, 5.1%). The prevalence of COPD was significantly higher in rural residents, elderly patients, smokers, in those with lower body mass index, less education, and poor ventilation in the kitchen, in those who were exposed to occupational dusts or biomass fuels, and in those with pulmonary problems in childhood and family history of pulmonary diseases. Among the patients who had COPD, 35.3% were asymptomatic; only 35.1 % reported lifetime diagnosis of bronchitis, emphysema, or other COPD; and only 6.5% have been tested with spirometry.

Conclusions: COPD is prevalent in individuals 40 years of age or older in China.

语种: 英语
WOS记录号: WOS:000250136400007
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/56771
Appears in Collections:北京大学第三临床医学院_期刊论文

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作者单位: 1.Tianjin Med Univ, Gen Hosp, Tianjin, Peoples R China
2.Peking Univ, Hosp 3, Beijing 100871, Peoples R China
3.Shenyang Mil Gen Hosp, Shenyang, Liaoning, Peoples R China
4.Guangzhou Med Coll, Affiliated Hosp 1, Guangzhou Inst Resp Dis, Guangzhou 510120, Guangdong, Peoples R China
5.Capital Univ Med Sci, Beijing Chaoyang Hosp, Beijing Inst Resp Med, Beijing, Peoples R China
6.China Med Univ, Affiliated Hosp 1, Shenyang, Liaoning, Peoples R China
7.Shanghai Jiao Tong Univ, Ruijing Hosp, Shanghai 200030, Peoples R China
8.Third Mil Med Univ, Xinqiao Hosp, Chongqing, Peoples R China
9.Fourth Mil Med Univ, Xijing Hosp, Xian 710032, Shanxi, Peoples R China
10.Jinan Univ, Affiliated Hosp 1, Guangzhou, Guangdong, Peoples R China
11.First Municipal People Hosp Shaoguan, Shaoguan, Guangdong, Peoples R China
12.Second Hosp Liwan Dist Guangzhou, Guangzhou, Guangdong, Peoples R China
13.Guangzhou Med Coll, Dept Epidemiol, Guangzhou, Guangdong, Peoples R China

Recommended Citation:
Zhong, Nanshan,Wang, Chen,Yao, Wanzhen,et al. Prevalence of chronic obstructive pulmonary disease in China - A large, population-based survey[J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE,2007,176(8):753-760.
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