IR@PKUHSC  > 北京大学第一临床医学院  > 皮肤性病科
学科主题临床医学
Animal Model of Dermatophytosis
Shimamura, Tsuyoshi1,2; Kubota, Nobuo2; Shibuya, Kazutoshi1,3
刊名JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
2012
DOI10.1155/2012/125384
收录类别SCI
文章类型Review
WOS标题词Science & Technology
类目[WOS]Biotechnology & Applied Microbiology ; Medicine, Research & Experimental
资助者Health Science Research Grants for Research on Emerging and Re-emerging Infectious Diseases ; Strategic Basis on Research Grounds for Non-governmental Schools at Heisei from Ministry of Education, Culture, Sports, Science and Technology of Japan ; Strategic Research Foundation from Ministry of Education, Culture, Sports, Science and Technology of Japan ; Pfizer Inc. ; Janssen Pharmaceutical K. K. ; Dainippon Sumitomo Pharma Co. ; Health Science Research Grants for Research on Emerging and Re-emerging Infectious Diseases ; Strategic Basis on Research Grounds for Non-governmental Schools at Heisei from Ministry of Education, Culture, Sports, Science and Technology of Japan ; Strategic Research Foundation from Ministry of Education, Culture, Sports, Science and Technology of Japan ; Pfizer Inc. ; Janssen Pharmaceutical K. K. ; Dainippon Sumitomo Pharma Co.
研究领域[WOS]Biotechnology & Applied Microbiology ; Research & Experimental Medicine
关键词[WOS]GUINEA-PIG MODEL ; EXPERIMENTAL TINEA-PEDIS ; TRICHOPHYTON-MENTAGROPHYTES-DERMATOPHYTOSIS ; IMIDAZOLE ANTIMYCOTIC AGENT ; TOPICAL ANTIFUNGAL AGENT ; THERAPEUTIC-EFFICACY ; IN-VITRO ; INVIVO ACTIVITY ; NAIL LACQUER ; BUTENAFINE HYDROCHLORIDE
英文摘要

Dermatophytosis is superficial fungal infection caused by dermatophytes that invade the keratinized tissue of humans and animals. Lesions from dermatophytosis exhibit an inflammatory reaction induced to eliminate the invading fungi by using the host′s normal immune function. Many scientists have attempted to establish an experimental animal model to elucidate the pathogenesis of human dermatophytosis and evaluate drug efficacy. However, current animal models have several issues. In the present paper, we surveyed reports about the methodology of the dermatophytosis animal model for tinea corporis, tinea pedis, and tinea unguium and discussed future prospects.

语种英语
资助者Health Science Research Grants for Research on Emerging and Re-emerging Infectious Diseases ; Strategic Basis on Research Grounds for Non-governmental Schools at Heisei from Ministry of Education, Culture, Sports, Science and Technology of Japan ; Strategic Research Foundation from Ministry of Education, Culture, Sports, Science and Technology of Japan ; Pfizer Inc. ; Janssen Pharmaceutical K. K. ; Dainippon Sumitomo Pharma Co. ; Health Science Research Grants for Research on Emerging and Re-emerging Infectious Diseases ; Strategic Basis on Research Grounds for Non-governmental Schools at Heisei from Ministry of Education, Culture, Sports, Science and Technology of Japan ; Strategic Research Foundation from Ministry of Education, Culture, Sports, Science and Technology of Japan ; Pfizer Inc. ; Janssen Pharmaceutical K. K. ; Dainippon Sumitomo Pharma Co.
WOS记录号WOS:000303722600001
引用统计
被引频次:14[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/56802
专题北京大学第一临床医学院_皮肤性病科
作者单位1.Toho Univ, Sch Med, Dept Surg Pathol, Ota Ku, Tokyo 1438541, Japan
2.POLA Pharma Inc, R&D Labs, Totsuka Ku, Yokohama, Kanagawa 2440812, Japan
3.Peking Univ, Hosp 1, Dept Dermatol, Beijing 100034, Peoples R China
推荐引用方式
GB/T 7714
Shimamura, Tsuyoshi,Kubota, Nobuo,Shibuya, Kazutoshi. Animal Model of Dermatophytosis[J]. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY,2012.
APA Shimamura, Tsuyoshi,Kubota, Nobuo,&Shibuya, Kazutoshi.(2012).Animal Model of Dermatophytosis.JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY.
MLA Shimamura, Tsuyoshi,et al."Animal Model of Dermatophytosis".JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2012).
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