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学科主题: 精神卫生
题名:
Prevalence of dementia in Latin America, India, and China: a population-based cross-sectional survey
作者: Rodriguez, Juan J. Llibre5; Ferri, Cleusa P.1; Acosta, Daisy6; Guerra, Mariella4,7; Huang, Yueqin8; Jacob, K. S.9; Krishnamoorthy, E. S.10; Salas, Aquiles11; Sosa, Ana Luisa12; Acosta, Isaac12; Dewey, Michael E.1; Gaona, Ciro13; Jotheeswaran, A. T.10; Li, Shuran8; Rodriguez, Diana4; Rodriguez, Guillermina3; Kumar, P. Senthil9; Valhuerdi, Adolfo2; Prince, Martin1; 10-66 Dementia Res Grp
刊名: LANCET
发表日期: 2008-08-09
DOI: 10.1016/S0140-6736(08)61002-8
卷: 372, 期:9637, 页:464-474
收录类别: SCI ; SSCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, General & Internal
研究领域[WOS]: General & Internal Medicine
关键词[WOS]: DEVELOPING-COUNTRIES ; ALZHEIMERS-DISEASE ; DIAGNOSTIC-CRITERIA ; AFRICAN-AMERICANS ; MENTAL-HEALTH ; 2 COMMUNITIES ; METAANALYSIS ; MORTALITY ; SUBTYPES ; NIGERIA
英文摘要:

Background Studies have suggested that the prevalence of dementia is lower in developing than in developed regions. We investigated the prevalence and severity of dementia in sites in low-income and middle-income countries according to two definitions of dementia diagnosis.

Methods We undertook one-phase cross-sectional surveys of all residents aged 65 years and older (n=14 960) in 11 sites in seven low-income and middle-income countries (China, India, Cuba, Dominican Republic, Venezuela, Mexico, and Peru). Dementia diagnosis was made according to the culturally and educationally sensitive, 10/66 dementia diagnostic algorithm, which had been prevalidated in 25 Latin American, Asian, and African centres; and by computerised application of the dementia criterion from the Diagnostic and Statistical Manual of Mental Disorders (DSM IV). We also compared prevalence of DSM-IV dementia in each of the study sites with that from estimates in European studies.

Findings The prevalence of DSM-IV dementia varied widely, from 0.3% (95% CI 0.1-0.5) in rural India to 6.3% (5.0-7.7) in Cuba. After standardisation for age and sex, DSM-IV prevalence in urban Latin American sites was four-fifths of that in Europe (standardised morbidity ratio 80 [95% CI 70-91]), but in China the prevalence was only half (56 [32-91] in rural China), and in India and rural Latin America a quarter or less of the European prevalence (18 [5-34] in rural India). 10/66 dementia prevalence was higher than that of DSM-IV dementia, and more consistent across sites, varying between 5.6% (95% CI 4.2-7.0) in rural China and 11.7% (10.3-13.1) in the Dominican Republic. The validity of the 847 of 1345 cases of 10/66 dementia not confirmed by DSM-IV was supported by high levels of associated disability (mean WHO Disability Assessment Schedule II score 33.7 [SD 28.6]).

Interpretation As compared with the 10/66 dementia algorithm, the DSM-IV dementia criterion might underestimate dementia prevalence, especially in regions with low awareness of this emerging public-health problem.

Funding Wellcome Trust (UK); WHO; the US Alzheimer′s Association; and Fondo Nacional De Ciencia, Y Tecnologia, Consejo De Desarrollo Cientifico Y Humanistico, and Universidad Central De Venezuela (Venezuela).

语种: 英语
WOS记录号: WOS:000258299000030
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/56837
Appears in Collections:北京大学精神卫生研究所_期刊论文

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作者单位: 1.Univ Hosp, Faustino Perez, Matanzas, Cuba
2.Inst Mem & Desordenes Relacionados, Lima, Peru
3.Med Univ Havana, Fac Med Finley Albarran, Havana, Cuba
4.Kings Coll London, Ctr Publ Mental Hlth, Hlth Serv & Populat Res Dept, Inst Psychiat, London SE5 8AF, England
5.Minist Protecc Social 6th Dist, Direcc Gen Salud Publ, Santo Domingo, Dominican Rep
6.Univ Nacl Pedro Henriquez Urena, Dept Internal Med, Geriatr Sect, Santo Domingo, Dominican Rep
7.Univ Peruana Cayetano Heredia, Lima, Peru
8.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
9.Christian Med Coll & Hosp, Vellore 632004, Tamil Nadu, India
10.Ctr Clin Neurosci, Inst Neurol Sci, Voluntary Hlth Serv, Madras, Tamil Nadu, India
11.Cent Univ Venezuela, Dept Med, Caracas Univ Hosp, Fac Med, Caracas, Venezuela
12.Univ Nacl Autonoma Mexico, Cognit & Behav Unit, Natl Inst Neurol & Neurosurg Mexico, Mexico City 04510, DF, Mexico
13.Clin Loira, Caracas, Venezuela

Recommended Citation:
Rodriguez, Juan J. Llibre,Ferri, Cleusa P.,Acosta, Daisy,et al. Prevalence of dementia in Latin America, India, and China: a population-based cross-sectional survey[J]. LANCET,2008,372(9637):464-474.
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