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学科主题: 临床医学
题名:
Comparative study of cardio-ankle vascular index between Chinese and Japanese healthy subjects
作者: Wang, Hongyu1; Shirai, Kohji2; Liu, Jinbo1; Lu, Na3; Wang, Min4; Zhao, Hongwei1; Xie, Jun4; Yu, Xiaolan1; Fu, Xiaobao1; Shi, Hongyan1; Li, Lihong1
关键词: Arterial stiffness ; arteriosclerosis ; cardio-ankle vascular index ; Chinese ; Japanese
刊名: CLINICAL AND EXPERIMENTAL HYPERTENSION
发表日期: 2014
DOI: 10.3109/10641963.2014.897715
卷: 36, 期:8, 页:596-601
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Pharmacology & Pharmacy ; Peripheral Vascular Disease
研究领域[WOS]: Pharmacology & Pharmacy ; Cardiovascular System & Cardiology
关键词[WOS]: PULSE-WAVE VELOCITY ; ARTERIAL STIFFNESS ; BLOOD-PRESSURE ; HYPERTENSION ; INDICATOR ; PARAMETER ; CAVI
英文摘要:

Objectives: Arterial stiffness is an independent predictor for vascular diseases. Cardio-ankle vascular index (CAVI) is a new index of arterial stiffness. However, there was little research about the CAVI value between different countries. The aim of the present study was to compare CAVI between Chinese and Japanese subjects and to assess related factors.

Methods: 2519 healthy persons [1245 Chinese (M/F, 524/721) and 1274 Japanese (M/F, 534/740)] from the Department of Physical Examination were enrolled into our study. CAVI was recorded using a VaseraVS-1000 vascular screening system.

Results: CAVI was increasing with aging in all subjects. CAVI was significantly lower in Chinese compared with Japanese both in male and female. There was difference in lipid metabolism between these two groups. Multivariate analysis showed that age, systolic blood pressure (SBP), fasting plasma glucose (FPG), plasma creatinine (Cr) were significant independent associating factors of CAVI in Chinese persons (beta = 0.548, p<0.001; beta = 0.129, p<0.001; beta = -0.105, p = 0.006; and beta = 0.100, p = 0.012, respectively), whereas age, SBP, high-density lipoprotein cholesterol (HDL-C), Cr, body mass index (BMI), FPG were significant independent associating p<0.001; beta = 0.090, p<0.001; beta = -0.124, p<0.001; beta = 0.055, p=0.009; respectively).

Conclusions: CAVI was increasing with aging in both Chinese and Japanese subjects. CAVI was significantly lower in Chinese than in Japanese subjects. Age, SBP, FPG and creatinine were independently associated with CAVI in both Chinese and Japanese subjects.

语种: 英语
所属项目编号: 2011-4026-02 ; 2010-Y002 ; 2012Y04
项目资助者: Capital Health Research and Development of Special ; hospital fund of Peking University Shougang Hospital
WOS记录号: WOS:000344605600012
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/56855
Appears in Collections:北京大学首钢医院_心血管内科_期刊论文

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作者单位: 1.Peking Univ, Dept Vasc Med, Shougang Hosp, Beijing 100144, Peoples R China
2.Toho Univ, Sch Med, Sakura Hosp, Dept Internal Med, Chiba 2748510, Japan
3.Beijing 6th Hosp, Dept Cardiol, Beijing, Peoples R China
4.Beijing Mentougou Dist Tradit Chinese Med Hosp, Dept Vasc Med, Beijing, Peoples R China

Recommended Citation:
Wang, Hongyu,Shirai, Kohji,Liu, Jinbo,et al. Comparative study of cardio-ankle vascular index between Chinese and Japanese healthy subjects[J]. CLINICAL AND EXPERIMENTAL HYPERTENSION,2014,36(8):596-601.
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