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IR@PKUHSC  > 北京大学第二临床医学院  > 血管外科  > 期刊论文
学科主题: 临床医学
题名:
Open and Endovascular Treatment of Trans-Atlantic Inter-Society Consensus II D Aortoiliac Occlusive Lesions: What Determines the Rate of Restenosis?
作者: Shen, Chen-Yang1; Liu, Yun-Feng2; Li, Qing-Le1; Zhang, Yong-Bao1; Jiao, Yang1; Krokidis, Miltiadis E.3; Zhang, Xiao-Ming1
关键词: Aortoiliac Occlusive Lesions ; Reconstruction ; Restenosis ; Risk Factor ; Trans-Atlantic Inter-Society Consensus II
刊名: CHINESE MEDICAL JOURNAL
发表日期: 2015-11-20
DOI: 10.4103/0366-6999.169053
卷: 128, 期:22, 页:3035-3042
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, General & Internal
研究领域[WOS]: General & Internal Medicine
关键词[WOS]: PERIPHERAL ARTERIAL-DISEASE ; LONG-TERM OUTCOMES ; SURGICAL RECONSTRUCTION ; AORTOBIFEMORAL BYPASS ; EXPANDABLE STENTS ; DIABETES-MELLITUS ; ILIAC ANGIOPLASTY ; TASC-II ; METAANALYSIS ; MANAGEMENT
英文摘要:

Background: Open surgery is the preferred approach for the treatment of type D lesions according to the Trans-Atlantic Inter-Society Consensus (TASC) II guideline, but endovascular solutions also appear to be a valid option in selected patients. The study aimed to identify the risk factors of restenosis after open and endovascular reconstruction of symptomatic TASC II D aortoiliac occlusive lesions (AIOLs).

Methods: Fifty-six patients (82 limbs) who underwent open repair and endovascular treatment (ET) for symptomatic TASC II D AIOLs between March 2005 and December 2012 were retrospectively reviewed. Baseline characteristics, preoperative and postoperative imaging, and operation procedure reports were reviewed and analyzed. Restenosis after revascularization was assessed by duplex ultrasound or computed tomography angiogram. Kaplan-Meier survival analysis, Log-rank test, and multivariate Cox regression were used to evaluate the relevance between risk factors and patency.

Results: The mean duration of follow-up was 42.8 +/- 23.5 months (ranging from 3 to 90 months). Primary patency rates at 1-, 3-, 5-, and 7-year were 93.6%, 89.3%, 87.0%, and 70.3%, respectively. Restenosis after revascularization occurred in 11 limbs. Kaplan-Meier survival analysis and the Log-rank test revealed that diabetes, Rutherford classification >= 5th and concurrent femoropopliteal TASC II type C/D lesions were significantly related to the duration of primary patency. According to the result of Cox regression, diabetes and femoropopliteal TASC II type C/D lesions were identified as the risk factors for restenosis after revascularization.

Conclusion: This study demonstrated that diabetes and femoropopliteal TASC II type C/D lesions are risk factors associated with restenosis after open and ET of TASC II D AIOLs.

语种: 英语
项目资助者: National Natural Science Foundation of China
WOS记录号: WOS:000365773400009
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/56863
Appears in Collections:北京大学第二临床医学院_血管外科_期刊论文

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作者单位: 1.Cambridge Univ Hosp NHS Trust, Dept Radiol, Cambridge CB2 0QQ, England
2.Peking Univ, Peoples Hosp, Dept Vasc Surg, Beijing 100044, Peoples R China
3.Peking Univ, Int Hosp, Dept Vasc Surg, Beijing 102206, Peoples R China

Recommended Citation:
Shen, Chen-Yang,Liu, Yun-Feng,Li, Qing-Le,et al. Open and Endovascular Treatment of Trans-Atlantic Inter-Society Consensus II D Aortoiliac Occlusive Lesions: What Determines the Rate of Restenosis?[J]. CHINESE MEDICAL JOURNAL,2015,128(22):3035-3042.
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