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IR@PKUHSC  > 北京大学第三临床医学院  > 运动医学研究所  > 期刊论文
学科主题: 临床医学
题名:
Evaluation of the Morphology and Osteogenic Potential of Titania-Based Electrospun Nanofibers
作者: Wang, Xiaokun1; Zhu, Jingxian2; Yin, Ling1; Liu, Shize1; Zhang, Xin2; Ao, Yingfang2; Chen, Haifeng1
刊名: JOURNAL OF NANOMATERIALS
发表日期: 2012
DOI: 10.1155/2012/959578
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary
研究领域[WOS]: Science & Technology - Other Topics ; Materials Science
关键词[WOS]: MECHANICAL-PROPERTIES ; FIBERS ; COMPOSITE ; DIFFERENTIATION ; OSTEOBLAST ; PARTICLES ; SCAFFOLDS ; COATINGS ; MESHES ; PHASE
英文摘要:

Submicron-scale titania-based ceramic fibers with various compositions have been prepared by electrospinning. The as-prepared nanofibers were heat-treated at 700 degrees C for 3 h to obtain pure inorganic fiber meshes. The results show that the diameter and morphology of the nanofibers are affected by starting polymer concentration and sol-gel composition. The titania and titania-silica nanofibers had the average diameter about 100-300 nm. The crystal phase varied from high-crystallized rutile-anatase mixed crystal to low-crystallized anatase with adding the silica addition. The morphology and crystal phase were evaluated by SEM and XRD. Bone-marrow-derived mesenchymal stem cells were seeded on titania-silica 50/50 fiber meshes. Cell number and early differentiation marker expressions were analyzed, and the results indicated osteogenic potential of the titania-silica 50/50 fiber meshes.

语种: 英语
所属项目编号: 2012CB933903 ; 2011AA030102
项目资助者: Ministry of Science and Technology of China ; Wallace H. Coulter Foundation
WOS记录号: WOS:000306023500001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/56884
Appears in Collections:北京大学第三临床医学院_运动医学研究所_期刊论文

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作者单位: 1.Peking Univ, Coll Engn, Dept Biomed Engn, Beijing 100871, Peoples R China
2.Peking Univ, Hosp 3, Inst Sports Med, Beijing 100191, Peoples R China

Recommended Citation:
Wang, Xiaokun,Zhu, Jingxian,Yin, Ling,et al. Evaluation of the Morphology and Osteogenic Potential of Titania-Based Electrospun Nanofibers[J]. JOURNAL OF NANOMATERIALS,2012.
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