北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第一临床医学院  > 期刊论文
学科主题: 临床医学
题名:
Analysis of risk factors of surgical site infections in breast cancer
作者: Gao Yang-xu; Xu Ling; Ye Jing-ming; Wang Dong-min; Zhao Jian-xin; Zhang Lan-bo; Duan Xue-ning; Liu Yin-hua
关键词: breast cancer ; adjuvant treatment ; surgical site infection
刊名: CHINESE MEDICAL JOURNAL
发表日期: 2010-03-05
DOI: 10.3760/cma.j.issn.0366-6999.2010.05.010
卷: 123, 期:5, 页:559-562
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, General & Internal
研究领域[WOS]: General & Internal Medicine
关键词[WOS]: NEOADJUVANT CHEMOTHERAPY
英文摘要:

Background Adjuvant chemotherapy has become an important component of standard therapy for breast cancer. However, until now, there have been few reports on the surgical site infections (SSI) after breast cancer surgery, specially after adjuvent chemotherapy. To study the risk factors of SSI of breast cancer, we analyzed patients diagnosed with breast cancer and treated with surgery.

Methods Fifty-five patients diagnosed with breast cancer and received breast conserving or modified radical operations in our hospital during January 2008 to March 2008 were selected. Factors (patients′ age, body mass index (BMI), diabetes mellitus, no or administered adjuvant chemotherapy, with or without onset of myelosuppression and the degree, surgical approaches, duration of operation, postoperative drainage duration and total drainage volume) associated with SSI were retrospectively reviewed and statistically analyzed by single factor analysis.

Results Five patients suffered SSI (5/55, 9.1%); nineteen receiving adjuvant chemotherapy experienced Grade III+ myelosuppression, among which 4 had SSI; only 1 out of the remaining 36 patients without adjuvant chemotherapy had SSI. The difference between the two groups was significant (P=0.043). The incidence of SSI in patients with postoperative drainage tube indwelling longer than 10 days was 5/21, whereas no SSI occurred in that less than 10 days (P=0.009). In our study, there was no significient difference in other associated factors.

Conclusions Concurrent Grade III+ myelosuppression after adjuvant chemotherapy is an important risk factor of SSI in breast cancer and needs further study. No SSI was detected with indwelling time of post operative drainage less than 10 days. Chin Med J 2010;123(5):559-562

语种: 英语
WOS记录号: WOS:000275740200010
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/56920
Appears in Collections:北京大学第一临床医学院_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: Peking Univ, Hosp 1, Ctr Breast Dis, Beijing 100034, Peoples R China

Recommended Citation:
Gao Yang-xu,Xu Ling,Ye Jing-ming,et al. Analysis of risk factors of surgical site infections in breast cancer[J]. CHINESE MEDICAL JOURNAL,2010,123(5):559-562.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Gao Yang-xu]'s Articles
[Xu Ling]'s Articles
[Ye Jing-ming]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Gao Yang-xu]‘s Articles
[Xu Ling]‘s Articles
[Ye Jing-ming]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace