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学科主题: 精神卫生
题名:
Population normative data for the 10/66 Dementia Research Group cognitive test battery from Latin America, India and China: a cross-sectional survey
作者: Luisa Sosa, Ana2; Albanese, Emiliano1; Prince, Martin1; Acosta, Daisy3; Ferri, Cleusa P.1; Guerra, Mariella4; Huang, Yueqin5; Jacob, K. S.7; Llibre de Rodriguez, Juan6; Salas, Aquiles8; Yang, Fang5; Gaona, Ciro9; Joteeshwaran, A. T.10; Rodriguez, Guillermina11; Rojas de la Torre, Gabriela2; Williams, Joseph D.10; Stewart, Robert1
刊名: BMC NEUROLOGY
发表日期: 2009-08-26
DOI: 10.1186/1471-2377-9-48
卷: 9
收录类别: SCI ; SSCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Clinical Neurology
研究领域[WOS]: Neurosciences & Neurology
关键词[WOS]: NEUROPSYCHOLOGICAL TEST-PERFORMANCE ; ALZHEIMERS-DISEASE CERAD ; DEVELOPING-COUNTRIES ; SCREENING INTERVIEW ; VERBAL FLUENCY ; DIAGNOSIS ; NORMS ; PREVALENCE ; CONSORTIUM ; EDUCATION
英文摘要:

Background: 1) To report site-specific normative values by age, sex and educational level for four components of the 10/66 Dementia Research Group cognitive test battery; 2) to estimate the main and interactive effects of age, sex, and educational level by site; and 3) to investigate the effect of site by region and by rural or urban location.

Methods: Population-based cross-sectional one phase catchment area surveys were conducted in Cuba, Dominican Republic, Venezuela, Peru, Mexico, China and India. The protocol included the administration of the Community Screening Instrument for Dementia (CSI ′D′, generating the COGSCORE measure of global function), and the Consortium to Establish a Registry for Alzheimer′s Disease (CERAD) verbal fluency (VF), word list memory (WLM, immediate recall) and recall (WLR, delayed recall) tests. Only those free of dementia were included in the analysis.

Results: Older people, and those with less education performed worse on all four tests. The effect of sex was much smaller and less consistent. There was a considerable effect of site after accounting for compositional differences in age, education and sex. Much of this was accounted for by the effect of region with Chinese participants performing better, and Indian participants worse, than those from Latin America. The effect of region was more prominent for VF and WLM than for COGSCORE and WLR.

Conclusion: Cognitive assessment is a basic element for dementia diagnosis. Age- and education-specific norms are required for this purpose, while the effect of gender can probably be ignored. The basis of cultural effects is poorly understood, but our findings serve to emphasise that normative data may not be safely generalised from one population to another with quite different characteristics. The minimal effects of region on COGSCORE and WLR are reassuring with respect to the cross-cultural validity of the 10/66 dementia diagnosis, which uses only these elements of the 10/66 battery.

语种: 英语
所属项目编号: GR066133 ; IIRG-04-1286
项目资助者: Wellcome Trust ; World Health Organisation ; US Alzheimer&prime ; s Association ; FONACIT/CDCH/UCV (Venezuela)
WOS记录号: WOS:000270557200001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/56940
Appears in Collections:北京大学精神卫生研究所_期刊论文

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作者单位: 1.Natl Inst Neurol & Neurosurg Mexico, Mexico City, DF, Mexico
2.Univ Nacl Pedro Henriquez Urena, Santo Domingo, Dominican Rep
3.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
4.Med Univ Havana, Fac Med Finley Albarran, Havana, Cuba
5.Clin Loira, Caracas, Venezuela
6.VHS, Community Hlth Serv, Madras, Tamil Nadu, India
7.Kings Coll London, Inst Psychiat, London WC2R 2LS, England
8.Univ Peruana Cayetano Heredia, Inst Memoria & Desordenes Relacionados, Lima, Peru
9.Christian Med Coll & Hosp, Vellore, Tamil Nadu, India
10.Cent Univ Venezuela, Hop Univ Caracas, Fac Med, Caracas, Venezuela
11.Direcc Gen Salud Publ Minist Protecc Social 6th D, Santo Domingo, Dominican Rep

Recommended Citation:
Luisa Sosa, Ana,Albanese, Emiliano,Prince, Martin,et al. Population normative data for the 10/66 Dementia Research Group cognitive test battery from Latin America, India and China: a cross-sectional survey[J]. BMC NEUROLOGY,2009,9.
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