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学科主题临床医学
Esophagogastric devascularization without splenectomy in portal hypertension: safe and effective?
Ni, Yan-Bin; Gao, Peng-Ji; Wang, Dong; Li, Zhao; Zhu, Ji-Ye
关键词Portal Hypertension Esophagogastric Devascularization Without Splenectomy Portal Vein System Thrombosis
刊名HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL
2015-06-15
DOI10.1016/S1499-3872(15)60328-9
14期:3页:276-280
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Gastroenterology & Hepatology
研究领域[WOS]Gastroenterology & Hepatology
关键词[WOS]GASTROESOPHAGEAL VARICES ; ESOPHAGEAL-VARICES ; SUGIURA PROCEDURE ; VEIN-THROMBOSIS ; CIRRHOSIS ; MANAGEMENT ; HEMORRHAGE
英文摘要

BACKGROUND: Esophagogastric variceal hemorrhage is a life-threatening complication of portal hypertension. In this study, we compared the therapeutic effect of a novel surgical procedure, esophagogastric devascularization without splenectomy (EDWS), with the widely used modified esophagogastric devascularization (MED) with splenectomy for the treatment of portal hypertension.

METHODS: Fifty-five patients with portal hypertension were included in this retrospective study. Among them, 27 patients underwent EDWS, and the other 28 patients underwent MED. Patients′ characteristics, perioperative parameters and long-term follow-up were analyzed.

RESULTS: The portal venous pressure was decreased by 20% postoperatively in both groups. The morbidity rate of portal venous system thrombosis in the EDWS group was significantly lower than that in the MED group (P=0.032). The land 3-year recurrence rates of esophagogastric variceal hemorrhage were 0% and 4.5% in the EDWS group, and 0% and 8.7% in the MED group, respectively (P=0.631).

CONCLUSIONS: EDWS is a safe and effective treatment for esophagogastric varices secondary to portal hypertension in selected patients. Patients treated with EDWS had a lower complication rate of portal venous system thrombosis compared with those treated with conventional MED.

语种英语
WOS记录号WOS:000355786700007
项目编号201002015
资助机构Health Industry Scientific Research Fund ; Beijing Medicine Research and Development Fund
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/57089
专题北京大学第二临床医学院_肝胆外科
作者单位Peking Univ, Peoples Hosp, Dept Hepatobiliary Surg, Beijing 100044, Peoples R China
推荐引用方式
GB/T 7714
Ni, Yan-Bin,Gao, Peng-Ji,Wang, Dong,et al. Esophagogastric devascularization without splenectomy in portal hypertension: safe and effective?[J]. HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL,2015,14(3):276-280.
APA Ni, Yan-Bin,Gao, Peng-Ji,Wang, Dong,Li, Zhao,&Zhu, Ji-Ye.(2015).Esophagogastric devascularization without splenectomy in portal hypertension: safe and effective?.HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL,14(3),276-280.
MLA Ni, Yan-Bin,et al."Esophagogastric devascularization without splenectomy in portal hypertension: safe and effective?".HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL 14.3(2015):276-280.
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