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学科主题: 临床医学
题名:
Esophagogastric devascularization without splenectomy in portal hypertension: safe and effective?
作者: Ni, Yan-Bin; Gao, Peng-Ji; Wang, Dong; Li, Zhao; Zhu, Ji-Ye
关键词: portal hypertension ; esophagogastric devascularization without splenectomy ; portal vein system thrombosis
刊名: HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL
发表日期: 2015-06-15
DOI: 10.1016/S1499-3872(15)60328-9
卷: 14, 期:3, 页:276-280
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Gastroenterology & Hepatology
研究领域[WOS]: Gastroenterology & Hepatology
关键词[WOS]: GASTROESOPHAGEAL VARICES ; ESOPHAGEAL-VARICES ; SUGIURA PROCEDURE ; VEIN-THROMBOSIS ; CIRRHOSIS ; MANAGEMENT ; HEMORRHAGE
英文摘要:

BACKGROUND: Esophagogastric variceal hemorrhage is a life-threatening complication of portal hypertension. In this study, we compared the therapeutic effect of a novel surgical procedure, esophagogastric devascularization without splenectomy (EDWS), with the widely used modified esophagogastric devascularization (MED) with splenectomy for the treatment of portal hypertension.

METHODS: Fifty-five patients with portal hypertension were included in this retrospective study. Among them, 27 patients underwent EDWS, and the other 28 patients underwent MED. Patients′ characteristics, perioperative parameters and long-term follow-up were analyzed.

RESULTS: The portal venous pressure was decreased by 20% postoperatively in both groups. The morbidity rate of portal venous system thrombosis in the EDWS group was significantly lower than that in the MED group (P=0.032). The land 3-year recurrence rates of esophagogastric variceal hemorrhage were 0% and 4.5% in the EDWS group, and 0% and 8.7% in the MED group, respectively (P=0.631).

CONCLUSIONS: EDWS is a safe and effective treatment for esophagogastric varices secondary to portal hypertension in selected patients. Patients treated with EDWS had a lower complication rate of portal venous system thrombosis compared with those treated with conventional MED.

语种: 英语
所属项目编号: 201002015
项目资助者: Health Industry Scientific Research Fund ; Beijing Medicine Research and Development Fund
WOS记录号: WOS:000355786700007
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/57089
Appears in Collections:北京大学第二临床医学院_肝胆外科_期刊论文

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作者单位: Peking Univ, Peoples Hosp, Dept Hepatobiliary Surg, Beijing 100044, Peoples R China

Recommended Citation:
Ni, Yan-Bin,Gao, Peng-Ji,Wang, Dong,et al. Esophagogastric devascularization without splenectomy in portal hypertension: safe and effective?[J]. HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL,2015,14(3):276-280.
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