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A pair of isomeric saponins with cytotoxicity from Albizzia julibrissin
Zou, K; Cui, JR; Wang, B; Zhao, YY; Zhang, RY
关键词Albizzia Julibrissin Triterpenoid Saponin Cytotoxicity Julibroside j(18) Julibroside j(19)
刊名JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
2005-12-01
DOI10.1080/10286020310001653246
7期:6页:783-789
收录类别SCI ; IC
文章类型Article
WOS标题词Science & Technology
类目[WOS]Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
关键词[WOS]ACACIA-VICTORIAE BENTHAM ; TRITERPENOID SAPONINS ; AVICINS ; FAMILY
英文摘要

Two new saponins have been isolated from the stem barks of Albizzia julibrissin Durazz, and their structures identified as 3-O-[beta-d-xylopyranosyl-(1 -> 2)-beta-d-fucopyranosyl-(1 -> 6)-beta-d-2-deoxy-2-acetoamidoglucopyranosyl]-21-O-{(6S)-2-trans-2-hydroxymethyl-6-methyl-6- O-[4-O-((6S)-2-trans-2-hydroxymethyl-6-hydroxy-6-methyl-2,7-octadienoyl)-beta-d-quinovopyranosyl]-2,7-octadienoyl}-acacic acid-28-O-beta-d-glucopyranosyl-(1 -> 3)-[alpha-l-arabinofuranosyl-(1 -> 4)]-alpha-l-rhamnopyranosyl-(1 -> 2)-beta-d-glucopyranosyl ester (1) and 3-O-[beta-d-xylopyranosyl-(1 -> 2)-beta-d-fucopyranosyl-(1 -> 6)-beta-d-2-deoxy-2-acetoamidoglucopyranosyl]-21-O-{(6S)-2-trans-2-hydroxymethyl-6-methyl-6- O-[3-O-((6S)-2-trans-2-hydroxymethyl-6-hydroxy-6-methyl-2,7-octadienoyl)-beta-d-quinovopyranosyl]-2,7-octadienoyl}acacic acid 28-O-beta-d-glucopyranosyl-(1 -> 3)-[alpha-l-arabinofuranosyl-(1 -> 4)]-alpha-l-rhamnopyranosyl-(1 -> 2)-beta-d-glucopyranosyl ester (2), based on chemical and spectral evidences, named as julibroside J 19 and julibroside J 18 , respectively. Both compounds show significant inhibition action against HeLa, Bel-7402 and MDA-MB-435 cancer cell lines in vitro .

语种英语
WOS记录号WOS:000233559500002
引用统计
被引频次:7[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/57090
专题北京大学药学院
作者单位1.China Three Gorges Univ, Coll Chem & Life Sci, Yichang 443000, Peoples R China
2.Peking Univ, Sch Pharmaceut Sci, Beijing 100083, Peoples R China
推荐引用方式
GB/T 7714
Zou, K,Cui, JR,Wang, B,et al. A pair of isomeric saponins with cytotoxicity from Albizzia julibrissin[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2005,7(6):783-789.
APA Zou, K,Cui, JR,Wang, B,Zhao, YY,&Zhang, RY.(2005).A pair of isomeric saponins with cytotoxicity from Albizzia julibrissin.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,7(6),783-789.
MLA Zou, K,et al."A pair of isomeric saponins with cytotoxicity from Albizzia julibrissin".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 7.6(2005):783-789.
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