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学科主题: 药学
题名:
A pair of isomeric saponins with cytotoxicity from Albizzia julibrissin
作者: Zou, K; Cui, JR; Wang, B; Zhao, YY; Zhang, RY
关键词: Albizzia julibrissin ; triterpenoid saponin ; cytotoxicity ; julibroside J(18) ; julibroside J(19)
刊名: JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
发表日期: 2005-12-01
DOI: 10.1080/10286020310001653246
卷: 7, 期:6, 页:783-789
收录类别: SCI ; IC
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]: Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
关键词[WOS]: ACACIA-VICTORIAE BENTHAM ; TRITERPENOID SAPONINS ; AVICINS ; FAMILY
英文摘要:

Two new saponins have been isolated from the stem barks of Albizzia julibrissin Durazz, and their structures identified as 3-O-[beta-d-xylopyranosyl-(1 -> 2)-beta-d-fucopyranosyl-(1 -> 6)-beta-d-2-deoxy-2-acetoamidoglucopyranosyl]-21-O-{(6S)-2-trans-2-hydroxymethyl-6-methyl-6- O-[4-O-((6S)-2-trans-2-hydroxymethyl-6-hydroxy-6-methyl-2,7-octadienoyl)-beta-d-quinovopyranosyl]-2,7-octadienoyl}-acacic acid-28-O-beta-d-glucopyranosyl-(1 -> 3)-[alpha-l-arabinofuranosyl-(1 -> 4)]-alpha-l-rhamnopyranosyl-(1 -> 2)-beta-d-glucopyranosyl ester (1) and 3-O-[beta-d-xylopyranosyl-(1 -> 2)-beta-d-fucopyranosyl-(1 -> 6)-beta-d-2-deoxy-2-acetoamidoglucopyranosyl]-21-O-{(6S)-2-trans-2-hydroxymethyl-6-methyl-6- O-[3-O-((6S)-2-trans-2-hydroxymethyl-6-hydroxy-6-methyl-2,7-octadienoyl)-beta-d-quinovopyranosyl]-2,7-octadienoyl}acacic acid 28-O-beta-d-glucopyranosyl-(1 -> 3)-[alpha-l-arabinofuranosyl-(1 -> 4)]-alpha-l-rhamnopyranosyl-(1 -> 2)-beta-d-glucopyranosyl ester (2), based on chemical and spectral evidences, named as julibroside J 19 and julibroside J 18 , respectively. Both compounds show significant inhibition action against HeLa, Bel-7402 and MDA-MB-435 cancer cell lines in vitro .

语种: 英语
WOS记录号: WOS:000233559500002
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/57090
Appears in Collections:北京大学药学院_期刊论文

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作者单位: 1.China Three Gorges Univ, Coll Chem & Life Sci, Yichang 443000, Peoples R China
2.Peking Univ, Sch Pharmaceut Sci, Beijing 100083, Peoples R China

Recommended Citation:
Zou, K,Cui, JR,Wang, B,et al. A pair of isomeric saponins with cytotoxicity from Albizzia julibrissin[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2005,7(6):783-789.
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