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Influence of erectile dysfunction course on its progress and efficacy of treatment with phosphodiesterase type 5 inhibitors
Liu De-feng; Jiang Hui; Hong Kai; Zhao Lian-ming; Tang Wen-hao; Ma Lu-lin
关键词Erectile Dysfunction Course Phosphodiesterase Type 5 Inhibitor International Index Oferectile Function
刊名CHINESE MEDICAL JOURNAL
2010-11-20
DOI10.3760/cma.j.issn.0366-6999.2010.22.016
123期:22页:3258-3261
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Medicine, General & Internal
研究领域[WOS]General & Internal Medicine
关键词[WOS]SILDENAFIL CITRATE ; PREVALENCE ; POPULATION ; IMPOTENCE ; SAFETY
英文摘要

Background Erectile dysfunction (ED) is a common impairment among older men, and the prevalence rates increase sharply after age of 60 years Most studies have focused on the prevalence rate or dangerouse factors The aim of this study was to investigate the basic epidemiologic data about ED patients with different ED courses The purpose of this researth was to understand the therapeutic effect of phosphodiesterase type 5 inhibitor (PDE5-I) and see how and why the ED course impact the progress of ED and the therapeutic effect of PDE5-I treatment

Methods From June 2008 to June 2009, 4252 questionnaires (Quality of Erection Questionnaire, QEQ) were gathered from 46 centers by urology or andrology doctors all around China Patients with ED (age 20 years) filled in first half of the questionnaires when they came for the first time, and then completed the second half 4 weeks after PDE5-I therapy

Results ED courses of most patients were less than 5 years (< 5 years, 740%, 5-10 years 20 8%, > 10 years, 52%) As ED course increasing, the incidence of the risk factors of ED, such as smoking, drinking, hypertension, diabetes, heart disease and hyperlipidemia also increase (P <= 0 01) PDE5-I was effective in improving the quality of sexual activities (P 50 01) Administration of PDE5-I improves satisfaction, enjoyment and frequency of sexual activities The longer the ED course, the worse the therapeutic effect (< 5 years, 96 1%, 5-10 years, 94 9%, > 10 years, 89 0%) (P <= 0 01)

Conclusions The ED course greatly affected the therapeutic effect of PDE5-1, the patients with ED should consult doctor at early stage of the disease Admistration of PDE5-I effectively improves the penile erection and the quality of sexual life of the patients hence should be considered as first-line medicine in the treatment of ED Chin Med J 2010,123(22) 3258-3261

语种英语
WOS记录号WOS:000284925300016
引用统计
被引频次:3[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/57118
专题北京大学第三临床医学院_泌尿外科
作者单位Peking Univ, Hosp 3, Dept Urol, Beijing 100191, Peoples R China
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GB/T 7714
Liu De-feng,Jiang Hui,Hong Kai,et al. Influence of erectile dysfunction course on its progress and efficacy of treatment with phosphodiesterase type 5 inhibitors[J]. CHINESE MEDICAL JOURNAL,2010,123(22):3258-3261.
APA Liu De-feng,Jiang Hui,Hong Kai,Zhao Lian-ming,Tang Wen-hao,&Ma Lu-lin.(2010).Influence of erectile dysfunction course on its progress and efficacy of treatment with phosphodiesterase type 5 inhibitors.CHINESE MEDICAL JOURNAL,123(22),3258-3261.
MLA Liu De-feng,et al."Influence of erectile dysfunction course on its progress and efficacy of treatment with phosphodiesterase type 5 inhibitors".CHINESE MEDICAL JOURNAL 123.22(2010):3258-3261.
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