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学科主题: 临床医学
题名:
A clinical and patch test study of patients with positive patch test reactions to fragrance mix in China
作者: Lu, XY; Li, LF; Wang, WH; Wang, J
关键词: allergy ; contact dermatitis ; fragrance ; fragrance mix ; patch test
刊名: CONTACT DERMATITIS
发表日期: 2005-04-01
卷: 52, 期:4, 页:188-191
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Allergy ; Dermatology
研究领域[WOS]: Allergy ; Dermatology
关键词[WOS]: DERMATITIS ; ALLERGY ; CONSTITUENTS ; POPULATION
英文摘要:

The clinical and patch test (PT) features of patients with positive PT reactions to fragrance mix (FM) were studied. 378 consecutive eczema outpatients patch tested with a modified European standard series were analysed. 60 patients (15.9%) reacted to FM. No significant differences could be found between the ages of FM PT-positive and PT-negative patients [median age 40.5 (range from 18 years to 69 years) versus median age 37.5 (range from 5 years to 81 years), rank sum test, P = 0.301]. FM PT-positive rate in confirmed non-cosmetic allergic contact dermatitis patients was 30.4%, which was similar to that in confirmed cosmetic allergic contact dermatitis patients (30.4% versus 30%, chi(2) test, chi(2) = 0.0010, P = 0.972). The FM PT-positive rates were 10.8% in males and 18.2% in females (chi(2) test, chi(2) = 3.3443, P = 0.067). 76.7% of the patients with fragrance contact dermatitis were allergic to Chinese traditional medicine, which is much higher than that for cosmetic allergy (76.7% versus 43.3%, chi(2) test, chi(2) = 6.9446, P = 0.008). The positive PT rate to colophonium in the patients with positive PT reactions to FM is higher than that in the FM PT-negative patients (18.9% versus 3.0%, chi(2) test, chi(2) = 15.5471, P < 0.01). 62.5% of the patients reacted to colophonium were positive to FM. These results show that age has little effect on fragrance contact allergy. Other fragrant products besides cosmetics are also important sources of fragrance contact allergy. Chinese traditional medicine was an important factor in fragrance allergy in China. Patients with positive PT reactions to FM are more likely to react to colophonium.

语种: 英语
WOS记录号: WOS:000228744700003
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/57172
Appears in Collections:北京大学第三临床医学院_皮肤科_期刊论文

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作者单位: Peking Univ, Hosp 3, Dept Dermatol, Beijing 100083, Peoples R China

Recommended Citation:
Lu, XY,Li, LF,Wang, WH,et al. A clinical and patch test study of patients with positive patch test reactions to fragrance mix in China[J]. CONTACT DERMATITIS,2005,52(4):188-191.
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