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Anti-inflammatory lignanamides from the roots of Solanum melongena L.
Sun, Jing1,2; Gu, Yu-Fan1,2; Su, Xiao-Qin1,2; Li, Man-Man1,2; Huo, Hui-Xia1,2; Zhang, Jing1,2; Zeng, Ke-Wu3; Zhang, Qian1; Zhao, Yun-Fang1; Li, Jun1; Tu, Peng-Fei1
关键词Solanaceae SoL.num MeL.ngena L. Lignanamide Anti-inflammation
刊名FITOTERAPIA
2014-10-01
DOI10.1016/j.fitote.2014.07.012
98页:110-116
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]Pharmacology & Pharmacy
关键词[WOS]NITRIC-OXIDE ; PHENOLIC-COMPOUNDS ; RABDOSIA-JAPONICA ; CANNABIS-SATIVA ; CAFFEIC ACID ; FRUITS ; NEOLIGNANS ; CONSTITUENTS ; INFLAMMATION ; ALKALOIDS
英文摘要

Four new lignanamides, melongenamides A-D (1-4), together with six known ones (5-10), were isolated from the roots of Solanum melongena L. Their structures were elucidated on the basis of 1D and 2D NMR experiments and by comparison of their spectroscopic and physical data with the literature values. Compounds 2-8 exhibited inhibitions of nitric oxide production in lipopolysaccharide-induced RAW 264.7 macrophages with IC50 values ranging from 16.2 to 58.5 mu M. (C) 2014 Elsevier B.V. All rights reserved.

语种英语
WOS记录号WOS:000343617600015
项目编号NCET-13-0693 ; CP2015
资助机构Program for New Century Excellent Talents in University ; Project of Standards Improvement of TCM ; Ministry of Industry and Information Technology of P.R. China
引用统计
被引频次:18[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/57183
专题北京大学药学院
北京大学药学院_天然药物学系
作者单位1.Beijing Univ Chinese Med, Modern Res Ctr Tradit Chinese Med, Beijing 100029, Peoples R China
2.Beijing Univ Chinese Med, Sch Chinese Mat Med, Beijing 100029, Peoples R China
3.Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Sun, Jing,Gu, Yu-Fan,Su, Xiao-Qin,et al. Anti-inflammatory lignanamides from the roots of Solanum melongena L.[J]. FITOTERAPIA,2014,98:110-116.
APA Sun, Jing.,Gu, Yu-Fan.,Su, Xiao-Qin.,Li, Man-Man.,Huo, Hui-Xia.,...&Tu, Peng-Fei.(2014).Anti-inflammatory lignanamides from the roots of Solanum melongena L..FITOTERAPIA,98,110-116.
MLA Sun, Jing,et al."Anti-inflammatory lignanamides from the roots of Solanum melongena L.".FITOTERAPIA 98(2014):110-116.
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