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学科主题: 临床医学
题名:
A Visualized Assay for Quercetin Based on the Formation of Silver-Gold Alloy Nanoparticles
作者: Chen, Zhanguang1; Zhang, Guoming1; Chen, Xi2; Chen, Junhui3; Fu, Zhuoxian1
关键词: Quercetin ; Gold nanoparticles ; Silver nanoparticles ; Alloy ; Visualized
刊名: PLASMONICS
发表日期: 2013-06-01
DOI: 10.1007/s11468-012-9376-y
卷: 8, 期:2, 页:201-207
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary
研究领域[WOS]: Chemistry ; Science & Technology - Other Topics ; Materials Science
关键词[WOS]: RESONANCE LIGHT-SCATTERING ; AU-AG ; IONS ; ELECTRODE ; LEAD
英文摘要:

A visualized assay for quercetin (QU) was first developed based on the formation of silver-gold alloy nanoparticles in this contribution. With the ability to reduce metal ions to metal substances, QU could reduce Ag+ absorbed on the surface of gold nanoparticles to metallic silver. The thickness of the formed Ag shell and the color change of the solution were proportional to the concentration of QU. Therefore, visualized detection of QU could be realized by studying the surface resonance plasmon absorption spectra of the analytical systems after addition of different concentration of QU. Under optimum conditions, trace amount of QU could be detected in the linear range 9.0x10(-7)-1.0x10(-4) mol L-1 with a detection limit of 6.5x10(-7) mol L-1. The present assay was applied in the determination of QU in human serum and satisfactory results were obtained. This assay is simple, rapid, and cost-effective, and it is a powerful complement for the spectroscopy assays for QU. Also, it is the first visualized spectroscopic assay of QU until now.

语种: 英语
所属项目编号: 2006B35630009 ; YR09009
项目资助者: Guangdong Science and Technology Department ; Science Foundation of Shantou University
WOS记录号: WOS:000320445700005
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/57212
Appears in Collections:北京大学深圳医院_期刊论文

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作者单位: 1.Shantou Univ, Dept Chem, Shantou 515063, Peoples R China
2.Guangdong Pharmaceut Univ, Guangzhou 510006, Guangdong, Peoples R China
3.Peking Univ, Dept Radiol, Shenzhen Hosp, Shenzhen 518036, Peoples R China

Recommended Citation:
Chen, Zhanguang,Zhang, Guoming,Chen, Xi,et al. A Visualized Assay for Quercetin Based on the Formation of Silver-Gold Alloy Nanoparticles[J]. PLASMONICS,2013,8(2):201-207.
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