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Expression of heat shock protein 20 inversely correlated with tumor progression in patients with ovarian cancer
Qiao, Naian1; Zhu, Yanhui2; Li, Haiying3; Qu, Zhongyu4; Xiao, Zhichun2
关键词Hsp20 Ovarian Cancer Tumor Progression
刊名EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY
2014
35期:5页:576-579
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Oncology ; Obstetrics & Gynecology
研究领域[WOS]Oncology ; Obstetrics & Gynecology
关键词[WOS]ISCHEMIA/REPERFUSION-INJURY ; HEAT-SHOCK-PROTEIN-20 ; HSP27 ; CELLS
英文摘要

Objective: To investigate a possible correlation between expression levels of heat shock protein 20 (HSP20) and tumor progression in patients with ovarian cancer. Materials and Methods: The study included 34 patients with ovarian cancer who were to undergo surgery, seven patients with ovarian carcinoid tumors, and five patients with normal ovaries as a control group. Ovarian tissues were obtained from patients by surgical resection and then analyzed by western blot. Results: Expression levels of HSP20 were inversely correlated with the grade of malignancy. Conclusion: The present findings suggest that HSP20 may play a protective role against the progression of ovarian cancer. Thus, HSP20 may represent a new target for the prediction and treatment of ovarian cancer.

语种英语
WOS记录号WOS:000346893300019
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/57220
专题北京大学医学信息学中心
作者单位1.Peking Univ, Med Informat Ctr, Beijing 100871, Peoples R China
2.Shandong Prov Hosp, Div Ultrasonog, Jinan, Peoples R China
3.Shandong Univ, Qilu Hosp, Dept Radiotherapy, Jinan 250100, Peoples R China
4.Shandong Univ, Qilu Hosp, Div Ultrasonog, Jinan 250100, Peoples R China
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GB/T 7714
Qiao, Naian,Zhu, Yanhui,Li, Haiying,et al. Expression of heat shock protein 20 inversely correlated with tumor progression in patients with ovarian cancer[J]. EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY,2014,35(5):576-579.
APA Qiao, Naian,Zhu, Yanhui,Li, Haiying,Qu, Zhongyu,&Xiao, Zhichun.(2014).Expression of heat shock protein 20 inversely correlated with tumor progression in patients with ovarian cancer.EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY,35(5),576-579.
MLA Qiao, Naian,et al."Expression of heat shock protein 20 inversely correlated with tumor progression in patients with ovarian cancer".EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY 35.5(2014):576-579.
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