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学科主题: 精神卫生
题名:
Adjunctive antidepressant prescriptions for hospitalized patients with schizophrenia in Asia (20012009)
作者: Xiang, Yu-Tao1,2; Ungvari, Gabor S.3; Wang, Chuan-Yue2; Si, Tian-Mei4,5; Lee, Edwin H. M.6; Chiu, Helen F. K.1; Lai, Kelly Y. C.1; He, Yan-Ling7; Yang, Shu-Yu8; Chong, Mian-Yoon9,10; Tan, Chay-Hoon11; Kua, Ee-Heok12; Fujii, Senta13; Sim, Kang14; Yong, Michael K. H.15; Trivedi, Jitendra K.16; Chung, Eun-Kee17; Udomratn, Pichet18; Chee, Kok-Yoon19; Sartorius, Norman20; Shinfuku, Naotaka21
关键词: antidepressant ; prescription pattern ; schizophrenia
刊名: ASIA-PACIFIC PSYCHIATRY
发表日期: 2013-06-01
DOI: 10.1111/j.1758-5872.2012.00231.x
卷: 5, 期:2, 页:E81-E87
收录类别: SCI ; SSCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Psychiatry
研究领域[WOS]: Psychiatry
关键词[WOS]: ANTIPSYCHOTIC POLYPHARMACY ; EAST-ASIA ; INPATIENTS ; SUICIDE
英文摘要:

Introduction Little is known about the prescription patterns of adjunctive antidepressants in Asian schizophrenia patients. This study aimed to examine trends in the use of antidepressants and their demographic and clinical correlates in the treatment of schizophrenia in Asia between 2001 and 2009. Methods A total of 6,761 hospitalized schizophrenia patients in nine Asian countries and territories were examined: 2,399 in 2001, 2,136 in 2004 and 2,226 in 2009. Patients′ socio-demographic and clinical characteristics and prescriptions of psychotropic drugs were recorded using a standardized protocol and data collection procedure. Results The proportion of antidepressant prescription was 6.8% in the whole sample; 5.3% in 2001, 6.5% in 2004 and 8.7% in 2009. There were wide inter-country variations at each survey ranging from 0.9% in Hong Kong to 15.3% in Singapore in 2001; from 1.9% in Korea to 15.4% in Singapore in 2004; and from 2.7% in Japan to 22.0% in Singapore in 2009. Multiple logistic regression analysis of the whole sample revealed that patients on antidepressants were younger, more likely to receive benzodiazepines and have significant extrapyramidal side-effects and less likely to have significant positive symptoms. Discussion Unlike findings in Western countries, adjunctive antidepressant prescription for schizophrenia was not common in Asia. The frequency of antidepressant prescription varied among countries and territories, suggesting that a host of clinical and socio-cultural factors played a role in determining antidepressant use in Asia.

语种: 英语
所属项目编号: 81171270 ; 30800367 ; 30770776 ; 2008B59 ; 2041454 ; CRC 249/2008 ; DOH92-NH-1025 ; CMRPG83043 ; 97001-62-010
项目资助者: National Natural Science Foundation of China ; Beijing Municipal Science and Technology Commission ; Chinese University of Hong Kong (Direct Grant for Research) ; Institute of Mental Health Research, Singapore ; Taiwan Bureau of National Health Insurance ; Chang Gung Memorial Hospital ; Taipei City Government in Taiwan
WOS记录号: WOS:000319401100010
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/57233
Appears in Collections:北京大学精神卫生研究所_期刊论文

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作者单位: 1.Chinese Univ Hong Kong, Dept Psychiat, Tai Po, Hong Kong, Peoples R China
2.Capital Med Univ, Beijing Anding Hosp, Mood Disorders Ctr, Beijing, Peoples R China
3.Univ Western Australia, Sch Psychiat & Clin Neurosci, Perth, WA 6009, Australia
4.Minist Mental Hlth, Key Lab Mental Hlth, Beijing, Peoples R China
5.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
6.Univ Hong Kong, Dept Psychiat, Hong Kong, Hong Kong, Peoples R China
7.Shanghai Mental Hlth Ctr, Dept Psychiat Epidemiol, Shanghai, Peoples R China
8.Taipei City Hosp, Dept Pharm, Taipei, Taiwan
9.Kaohsiung Chang Gung Mem Hosp, Kaohsiung, Taiwan
10.Chang Gung Univ, Sch Med, Kaohsiung, Taiwan
11.Natl Univ Singapore, Dept Pharmacol, Singapore 117548, Singapore
12.Natl Univ Singapore, Dept Psychol Med, Singapore 117548, Singapore
13.HITS, Kobe, Hyogo, Japan
14.Inst Mental Hlth, Dept Gen Psychiat, Buangkok View, Singapore
15.Alexandra Hosp, Jurong Hlth Serv, Dept Med, Singapore, Singapore
16.CSM Med Univ UP, Dept Psychiat, Lucknow, Uttar Pradesh, India
17.Natl Seoul Hosp, Dept Psychiat, Seoul, South Korea
18.Assoc Improvement Mental Hlth Programs, Geneva, Switzerland
19.Seinan Gakuin Univ, Sch Human Sci, Dept Social Welf, Fukuoka, Japan
20.Prince Songkla Univ, Fac Med, Dept Psychiat, Hat Yai, Thailand
21.Kuala Lumpur Hosp, Tunku Abdul Rahman Inst Neurosci, Dept Psychiat & Mental Hlth, Kuala Lumpur, Malaysia

Recommended Citation:
Xiang, Yu-Tao,Ungvari, Gabor S.,Wang, Chuan-Yue,et al. Adjunctive antidepressant prescriptions for hospitalized patients with schizophrenia in Asia (20012009)[J]. ASIA-PACIFIC PSYCHIATRY,2013,5(2):E81-E87.
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