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学科主题: 基础医学
题名:
Cytopathologic Analysis of Stroma-Poor Salivary Gland Epithelial/Myoepithelial Neoplasms on Fine Needle Aspiration
作者: Chen, Longwen1; Ray, Nancy1; He, Huiying2; Hoschar, Aaron1
关键词: Epithelial/myoepithelial neoplasm ; No or rare stroma ; Salivary gland fine needle aspiration
刊名: ACTA CYTOLOGICA
发表日期: 2012
DOI: 10.1159/000333563
卷: 56, 期:1, 页:25-33
收录类别: SCI
文章类型: Article
关键词[WOS]: EPITHELIAL-MYOEPITHELIAL CARCINOMA ; ADENOID CYSTIC CARCINOMA ; PLEOMORPHIC ADENOMA ; DIAGNOSTIC PITFALLS ; CYTOLOGY ; LESIONS ; TUMORS ; BIOPSY
英文摘要:

Objective: Fine needle aspiration (FNA) diagnosis of salivary gland neoplasms with epithelial/myoepithelial cells but rare or no stroma is usually difficult. Our aim was to study the cytomorphology of this cohort of FNA cases and evaluate the clinical follow-up. Study Design: The diagnostic terminology for this group of aspirates was ′favor an epithelial/myoepithelial neoplasm of the salivary gland′. The cytologic smears of 32 such cases were retrieved and showed cellular smears with bland-appearing or mildly atypical epithelial and myoepithelial cells without typical chondromyxoid stroma seen in pleomorphic adenoma (PA). Results: Twenty of the 32 cases had histologic follow-up. Ten of these 20 cases were PAs, including 8 cellular PAs. Two cases were basal cell adenomas, 1 case myoepithelioma and 1 case benign adenoma, not otherwise specified. Among the 6 malignant tumors on surgical resections, there were 3 epithelial-myoepithelial carcinomas, 1 myoepithelial carcinoma, 1 basal cell adenocarcinoma and 1 adenoid cystic carcinoma. Conclusions: Although 14 of the 20 (70%) cases were benign neoplasms, a substantial amount of cases (30%) were malignant salivary gland neoplasms. The generic diagnostic terminology of ′epithelial/myoepithelial neoplasm of the salivary gland′ and appropriate clinical follow-up are recommended for these cases. Copyright (C) 2012 S. Karger AG, Basel

语种: 英语
WOS记录号: WOS:000299390500003
Citation statistics:
内容类型: 期刊论文
版本: 出版稿
URI标识: http://ir.bjmu.edu.cn/handle/400002259/57310
Appears in Collections:基础医学院_病理学系_期刊论文

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作者单位: 1.Cleveland Clin, Dept Anat Pathol, Cleveland, OH 44195 USA
2.Peking Univ, Hlth Sci Ctr, Dept Pathol, Beijing 100871, Peoples R China

Recommended Citation:
Chen, Longwen,Ray, Nancy,He, Huiying,et al. Cytopathologic Analysis of Stroma-Poor Salivary Gland Epithelial/Myoepithelial Neoplasms on Fine Needle Aspiration[J]. ACTA CYTOLOGICA,2012,56(1):25-33.
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