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学科主题: 临床医学
题名:
Laparoscopic total pelvic exenteration for pelvic malignancies: the technique and short-time outcome of 11 cases
作者: Yang, Kunlin1,2,3; Cai, Lin1,2,3; Yao, Lin1,2,3; Zhang, Zheng1,2,3; Zhang, Cuijian1,2,3; Wang, Xin4,5; Tang, Jianqiang4,5; Li, Xuesong1,2,3; He, Zhisong1,2,3; Zhou, Liqun1,2,3
关键词: Laparoscopic ; Total pelvic exenteration ; Pelvic malignancy ; Reconstruction
刊名: WORLD JOURNAL OF SURGICAL ONCOLOGY
发表日期: 2015-10-15
DOI: 10.1186/s12957-015-0715-2
卷: 13
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Oncology ; Surgery
研究领域[WOS]: Oncology ; Surgery
关键词[WOS]: RECURRENT RECTAL-CANCER ; BARRELED WET COLOSTOMY ; ADVANCED COLORECTAL-CARCINOMA ; COLON-CANCER ; SINGLE INSTITUTION ; CERVICAL-CANCER ; OPEN COLECTOMY ; ILEAL CONDUIT ; OPEN SURGERY ; FOLLOW-UP
英文摘要:

Background: Previous reports about laparoscopic total pelvic exenteration (LTPE) are still limited. In the present study, we described our single-center experience of the initial 11 cases.

Methods: Between April 2011 and September 2015, eight males and three females diagnosed as pelvic malignancies underwent LTPE by the same operation team. We retrospectively collected all cases′ parameters about surgical technique. Thirty-seven patients who received open surgery were also retrospectively collected. A comparison between LTPE and open surgery was performed to evaluate the feasibility and safety of LTPE.

Results: Eleven cases successfully underwent the LTPE without any intraoperative complication. No open conversion was required. Eight patients underwent Bricker′s procedure. Three patients were performed with the cutaneous ureterostomy. Anus preservation operation was performed in three patients. Compared with open surgery, LTPE had longer mean operative time (565.2 vs 468.2 min, p = 0.004) but less mean blood loss (547.3 vs 1033.0 ml, p < 0.001) and shorter postoperative hospitalization time (15.3 vs 22.4 days, p = 0.004). One patient died of pulmonary embolism in the 7th month of follow-up time. One patient died of recurrence in the 12th month of follow-up time. Nine patients are still alive without recurrence and metastasis. The mean follow-up time was 11.1 months.

Conclusions: The technique of LTPE seems to be feasible and safe in the treatment of carefully selected patients of pelvic malignancies. LTPE can also decrease the blood loss, the recovery time, and the hospital stay. But the oncological safety and long-term outcome of LTPE still need to be explored.

语种: 英语
所属项目编号: 81272710
项目资助者: Natural Science Foundation of China
WOS记录号: WOS:000362875000001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/57387
Appears in Collections:北京大学第一临床医学院_泌尿外科_期刊论文

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作者单位: 1.Peking Univ, Dept Urol, Hosp 1, Beijing 100034, Peoples R China
2.Peking Univ, Inst Urol, Beijing 100034, Peoples R China
3.Natl Urol Canc Ctr, Beijing 100034, Peoples R China
4.Peking Univ, Hosp 1, Dept Gen Surg, Beijing 100034, Peoples R China
5.Peking Univ, Inst Gen Surg, Hosp 1, Beijing 100034, Peoples R China

Recommended Citation:
Yang, Kunlin,Cai, Lin,Yao, Lin,et al. Laparoscopic total pelvic exenteration for pelvic malignancies: the technique and short-time outcome of 11 cases[J]. WORLD JOURNAL OF SURGICAL ONCOLOGY,2015,13.
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