IR@PKUHSC  > 北京大学药学院
学科主题药学
Determination of absolute configuration of alpha-hydroxy ketones using NMR
Yang Chun-Hui; Chen Jing-Wen; Li Qin; Peng Kun; Pan Xin-Fu; Cui Yu-Xin
关键词Alpha-hydroxy Ketones Absolute Configuration Mosher&Prime s Method Nmr
刊名CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
2006-07-01
27期:7页:1295-1297
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Multidisciplinary
研究领域[WOS]Chemistry
关键词[WOS]OXIDATION
英文摘要

alpha-Hydroxy ketones are frequently involved in biologically important compounds and, therefore, the determination of the stereochemistry of these structural elements has attracted the attention in natural products′ chemistry. In this paper a simpler Mosher′s method was developed from the modified Mosher′s method. It only need one configuration of MTPA to determine the absolute configurations of four a-hydroxy ketones with their (S)- and (R)-MTPA esters using H-1 NMR. The signals of protons on the same side with phenyl ring will be in the higher field than those of on the different side ones. Consequently according to the model the main configuration of compounds 1, 2, 3 and 4 were determined as S, R, R and S, respectively.

语种中文
WOS记录号WOS:000239259000027
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/57396
专题北京大学药学院
作者单位1.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China
2.Lanzhou Univ, Dept Chem, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
3.Peking Univ, Med & Healthy Anal Ctr, Beijing 100083, Peoples R China
推荐引用方式
GB/T 7714
Yang Chun-Hui,Chen Jing-Wen,Li Qin,et al. Determination of absolute configuration of alpha-hydroxy ketones using NMR[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2006,27(7):1295-1297.
APA Yang Chun-Hui,Chen Jing-Wen,Li Qin,Peng Kun,Pan Xin-Fu,&Cui Yu-Xin.(2006).Determination of absolute configuration of alpha-hydroxy ketones using NMR.CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,27(7),1295-1297.
MLA Yang Chun-Hui,et al."Determination of absolute configuration of alpha-hydroxy ketones using NMR".CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 27.7(2006):1295-1297.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Yang Chun-Hui]的文章
[Chen Jing-Wen]的文章
[Li Qin]的文章
百度学术
百度学术中相似的文章
[Yang Chun-Hui]的文章
[Chen Jing-Wen]的文章
[Li Qin]的文章
必应学术
必应学术中相似的文章
[Yang Chun-Hui]的文章
[Chen Jing-Wen]的文章
[Li Qin]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。