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学科主题: 口腔医学
题名:
Dental pulp stem cells
作者: Liu, He; Gronthos, Stan; Shi, Songtao; Klimanskaya, I; Lanza, R
刊名: ADULT STEM CELLS
发表日期: 2006
DOI: 10.1016/S0076-6879(06)19005-9
卷: 419, 页:99-113
收录类别: BSCI ; SCI
文章类型: Book Chapter
WOS标题词: Science & Technology
类目[WOS]: Biochemical Research Methods ; Biochemistry & Molecular Biology
研究领域[WOS]: Biochemistry & Molecular Biology
关键词[WOS]: HUMAN-BONE-MARROW ; EXTRACELLULAR-MATRIX PROTEINS ; ODONTOBLAST-LIKE CELLS ; IN-VITRO ; GENE-EXPRESSION ; MORPHOGENETIC PROTEIN-2 ; SEQUENCE DETERMINATION ; ALKALINE-PHOSPHATASE ; STROMAL FIBROBLASTS ; REPAIR RESPONSES
英文摘要:

Postnatal stem cells have been isolated from a variety of tissues. These stem cells are thought to possess great therapeutic potential for repairing damaged and/or defective tissues. Clinically, hematopoietic stem cells have been successfully used for decades in the treatment of various diseases and disorders. However, the therapeutic potential of other postnatal stem cell populations has yet to be realized, because of the lack of detailed understanding of their stem cell characteristics at the cellular and molecular levels. Furthermore, there is limited knowledge of their therapeutic value at the preclinical level. Therefore, it is necessary to develop optimal strategies and approaches to overcome the substantial challenges currently faced by researchers examining the clinical efficacy of different postnatal stem cell populations. In this review, we introduce methodologies for isolating postnatal stem cells from human dental pulp and discuss their potential role in tissue regeneration.

语种: 英语
WOS记录号: WOS:000242860600005
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/57425
Appears in Collections:北京大学口腔医学院_期刊论文

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作者单位: 1.Peking Univ, Sch Stomatol, Beijing, Peoples R China
2.Univ So Calif, Sch Dent, Ctr Craniofacial Mol Biol, Los Angeles, CA 90033 USA

Recommended Citation:
Liu, He,Gronthos, Stan,Shi, Songtao,et al. Dental pulp stem cells[J]. ADULT STEM CELLS,2006,419:99-113.
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