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学科主题临床医学
A PRECLINICAL IN VIVO INVESTIGATION OF HIGH-INTENSITY FOCUSED ULTRASOUND COMBINED WITH RADIOTHERAPY
Liu, Chao-Xing1; Gao, Xian-Shu1; Xiong, Liu-Lin3; Ge, Hui-Yu4; He, Xin-Yong1; Li, Ting2; Zhang, Hong-Juan5; Bai, Hong-Zhong6; Lin, Qiang1; Zhang, Ming1; Zhao, Jing1; Xiong, Wei1; Bai, Yu; Asaumi, Junichi7
关键词High-intensity Focused Ultrasound (Hifu) Radiotherapy (Rt) Swine Pancreas Injury
刊名ULTRASOUND IN MEDICINE AND BIOLOGY
2011
DOI10.1016/j.ultrasmedbio.2010.10.001
37期:1页:69-77
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Acoustics ; Radiology, Nuclear Medicine & Medical Imaging
资助者Ministry of Health of the People&prime ; s Republic of China ; Ministry of Health of the People&prime ; s Republic of China
研究领域[WOS]Acoustics ; Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]PROSTATE-CANCER ; BREAST-CANCER ; THERAPY ; ABLATION ; HIFU
英文摘要

This study aims to perform an in vivo investigation evaluating the injury to the pancreas and adjacent tissue of swine resulting with high-intensity focused ultrasound (HIFU) combined with radiotherapy (RT). The protocol was approved by the animal ethics committee at the Peking University First Hospital. A total of 12 domestic swine were divided into four groups: control, HIFU only, RT only and HIFU + RT. The injury to the pancreas, adjacent tissue and tissue within the acoustic path of the HIFU beam was assessed based on gross and histologic findings. For the targeted region of the pancreas, the score of the combined group was higher than that of the HIFU group and there was significant difference. For the acoustic path tissue, there was no significant difference except between the control group and the other groups. HIFU combined with RT increased the injury to the targeted pancreas, without increased injury to tissue outside of the targeted region. (E-mail: xsgao777@hotmail.com) (C) 2011 Published by Elsevier Inc. on behalf of World Federation for Ultrasound in Medicine & Biology.

语种英语
所属项目编号WKJ2006-1-007
资助者Ministry of Health of the People&prime ; s Republic of China ; Ministry of Health of the People&prime ; s Republic of China
WOS记录号WOS:000285083600010
引用统计
被引频次:5[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/57522
专题北京大学第一临床医学院_肿瘤化疗科
作者单位1.Peking Univ, Hosp 1, Dept Radiat Oncol, Beijing 100034, Peoples R China
2.Peking Univ, Hosp 1, Dept Pathol, Beijing 100034, Peoples R China
3.Peking Univ, Peoples Hosp, Dept Urol, Beijing 100034, Peoples R China
4.Peking Univ, Hosp 3, Dept Ultrasound, Beijing 100871, Peoples R China
5.First Hosp Shijiazhuang City, Dept Radiat Oncol, Shijiazhuang, Hebei Province, Peoples R China
6.Hebei Chest Hosp, Dept Radiol, Shijiazhuang, Peoples R China
7.Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Oral & Maxillofacial Radiol, Okayama, Japan
推荐引用方式
GB/T 7714
Liu, Chao-Xing,Gao, Xian-Shu,Xiong, Liu-Lin,et al. A PRECLINICAL IN VIVO INVESTIGATION OF HIGH-INTENSITY FOCUSED ULTRASOUND COMBINED WITH RADIOTHERAPY[J]. ULTRASOUND IN MEDICINE AND BIOLOGY,2011,37(1):69-77.
APA Liu, Chao-Xing.,Gao, Xian-Shu.,Xiong, Liu-Lin.,Ge, Hui-Yu.,He, Xin-Yong.,...&Asaumi, Junichi.(2011).A PRECLINICAL IN VIVO INVESTIGATION OF HIGH-INTENSITY FOCUSED ULTRASOUND COMBINED WITH RADIOTHERAPY.ULTRASOUND IN MEDICINE AND BIOLOGY,37(1),69-77.
MLA Liu, Chao-Xing,et al."A PRECLINICAL IN VIVO INVESTIGATION OF HIGH-INTENSITY FOCUSED ULTRASOUND COMBINED WITH RADIOTHERAPY".ULTRASOUND IN MEDICINE AND BIOLOGY 37.1(2011):69-77.
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